Membrane Fusion in Macrophage Function

巨噬细胞功能中的膜融合

• 批准号: nhmrc : 631584
• 负责人: A/Pr Rohan Teasdale
• 金额: $ 36.19万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/membrane-fusion-macrophage-function/101238
• 关键词: Membrane; Fusion; Macrophage; Function

Macrophages are important cells at the front-line of immunity where one of their main roles is to release anti-bacterial proteins. We will study the macrophage molecules, subcellular organelles and pathways that help to release these proteins to kill bacteria and fight infection. Our studies will identify new cellular targets for boosting immunity and treating inherited diseases with defective macrophage function.

巨噬细胞是免疫前线的重要细胞，其主要作用之一是释放抗菌蛋白。我们将研究巨噬细胞分子，亚细胞器和有助于释放这些蛋白质以杀死细菌和对抗感染的途径。我们的研究将确定新的细胞靶点，用于增强免疫力和治疗巨噬细胞功能缺陷的遗传性疾病。