Fighting infection: exploiting host-pathogen interactions

对抗感染：利用宿主与病原体的相互作用

• 批准号: nhmrc : 606788
• 负责人: A/Pr Rohan Teasdale
• 金额: $ 636.85万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/fighting-infection-exploiting-pathogen-interactions/97611
• 关键词: Fighting; infection; exploiting; host; pathogen

This program will investigate the strategies used by pathogenic bacteria to cause human diseases. The research will focus on how bacteria initiate infections, how they invade, cause cell and tissue damage and respond to their human host. It will also examine how the host’s innate immune system interacts with these bacteria. The results will provide new insights into host-pathogen interactions and reveal new targets for the development of novel antibacterial drugs and vaccines.

本节目将调查致病细菌引起人类疾病的策略。这项研究将集中在细菌如何发起感染，它们如何入侵，造成细胞和组织损伤，以及对人类宿主的反应。它还将检查宿主的先天性免疫系统如何与这些细菌相互作用。这一结果将为宿主-病原体的相互作用提供新的见解，并为新型抗菌药物和疫苗的开发提供新的靶点。