The cell biology of macropinocytosis pathways in antigen presenting cells
The cell biology of macropinocytosis pathways in antigen presenting cells
批准号:
nhmrc : 566727
负责人:
A/Pr Rohan Teasdale
金额:
$36.36万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
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英文摘要
Cells internalise molecules in membrane-bound vesicles, a process known as endocytosis. This internalisation pathway is essential for many biological events, including the ability to capture foreign antigens and mount an effective immune response. Some internalisation pathways can be switched on by signals received at the cell surface. This study will identify the molecules that control antigen capture in immune cells. This knowledge is important for the development of better vaccines.
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