Gastrointestinal Diseases Training Grant

描述（由申请人提供）： 目的：科罗拉多大学健康科学中心的胃肠病学和肝病学培训计划致力于为胃肠研究的调查职业准备高度积极的博士后候选人。在持续科学成就的29年背景的基础上，该计划已经开始了一个令人兴奋的新增长时期，自上次审查该申请以来，培训机会不断扩大。这种增长的特点是新的研究人员的招聘，新的NIH（和其他）赠款的成功竞争，并利用先进的分子和生物物理技术，以解决胃肠道研究的基本问题的程序的发展。此外，正式课程的可用性已经扩大;临床，转化和成果研究的机会已经增加，并已开发了重要的新研究项目，以提高培训的广度和质量。这些智力和资本资源为每年两名新受训人员的职业发展创造了良好的环境。我们建议把每名学员的培训期由2年延长至3年，以配合课程和研究经验，使有志于学术事业的学员能取得成功。 资源：该计划的核心是由32名杰出的教师（19名MD，3名MD博士和10名博士）提供，其研究兴趣围绕三大主题，包括i）胃肠道和肝脏组织的细胞和分子生物学ii）营养和致癌作用iii）肝炎，肝移植和胃肠内窥镜检查的临床试验和结果。教师的专业知识范围从基础科学到临床，转化，结果和行为调查。培训教师参与7个主要中心，6个项目，93个个人校外赠款。这些资源使学员有机会从临床，行为，流行病学，生理，生物化学，分子和遗传学的角度来探讨胃肠道疾病。学员可以选择在培训期间获得证书，硕士或博士学位。 项目：与胃肠病学的成人和儿科部门的领导的建议，执行委员会提供了该计划的总体方向和战略规划。该学院广泛借鉴国家认可的研究和培训计划，在其他部门和部门提供最好的培训机会。每年从临床和基础科学学科的奖学金和博士课程中招募两名学员。选择是基于对以研究为导向的职业的确认承诺，综合研究培训计划，以及在感兴趣的领域具有既定证书的适当教师的支持，以确保最佳的科学和职业指导。该计划的长期目标是识别和支持致力于胃肠道研究严格培训的新研究人员，并继续培养未来的科学和学术领导者。

DESCRIPTION (provided by applicant): Purpose: The Training Program in Gastroenterology and Hepatology at the University of Colorado Health Sciences Center is committed to preparing highly motivated post-doctoral candidates for investigative careers in gastrointestinal research. Building on a 29 year background of sustained scientific accomplishment, the program has embarked on an exciting period of new growth and expansion of training opportunities since this application was last reviewed. This growth is marked by the recruitment of new research faculty, the successful competition for new NIH (and other) grants, and the development of programs that utilize sophisticated molecular and biophysical technologies to address basic issues in gastrointestinal research. Further, the availability of-formal coursework has been expanded; clinical, translational and outcomes research opportunities have been increased and significant new research programs have been developed to enhance the breadth and quality of training. These intellectual and capital resources contribute to an outstanding environment for career development of two new trainees per year. We propose to extend the period of training from 2 to 3 years for each trainee to accommodate the coursework and research experience that is necessary for a committed trainee to be successful in an academic career. Resources: The nucleus of the program is provided by 32 distinguished faculty members (19 MD, 3 MD PhD, and 10PhD) with research interests centered around three major themes, including i) cell and molecular biology of gastrointestinal and liver tissues ii) nutrition and carcinogenesis and iii) clinical trials and outcomes in hepatitis, liver transplantation and gastrointestinal endoscopy. The expertise of the faculty ranges from fundamental basic science to clinical, translational, outcomes and behavioral investigation. The training faculty participate in 7 major center, 6 project, and 93 individual extramural grants. These resources allow trainees an opportunity to approach gastrointestinal diseases from clinical, behavioral, epidemiologic, physiologic, biochemical, molecular and genetic perspectives. Trainees may elect to earn a Certificate, Masters or PhD degree during their training. Program: With the advice of the leadership of the adult and pediatric Divisions of Gastroenterology, the Executive Committee provides the overall direction and strategic planning for the program. The faculty draws broadly from nationally recognized research and training programs in other Divisions and Departments to provide the best training opportunities possible. Each year, two trainees are recruited from fellowship and doctoral programs in both clinical and basic science disciplines. Selection is based upon a confirmed commitment to a research-oriented career, an integrated research training plan, and the support of appropriate faculty with established credentials in the field of interest to ensure optimal scientific and career mentoring. The long-term goal of this program is to identify and support new investigators committed to rigorous training in gastrointestinal research, and to continue to develop the scientific and academic leaders for the future.