University of Louisville Cagewash Modernization

路易斯维尔大学笼洗现代化

• 批准号: 10736321
• 负责人: Leslie C. Sherwood
• 金额: $ 30.64万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10736321
• 关键词: 20 year old; Alcohols; Allergens; Animal Experimentation; Animals; Appalachian Region; Area; Award; Basic Science; Cardiovascular system; Cell Nucleus; Censuses; Centers of Research Excellence; Development; Electronic cigarette; Employment; Equipment; Friends; Funding; Grant; Growth; Health; Health Sciences; Inflammation; Inhalation; Institution; Kentucky; Maintenance; Microcomputers; Mission; Modeling; Modernization; National Institute of General Medical Sciences; Occupational Health; Phase; Population; Research; Research Personnel; Rodent; Science; Strategic Planning; Superfund; Technology; Toxicology; Toxin; United States National Institutes of Health; Universities; animal facility; cancer immunotherapy; cardiometabolism; cigarette smoke; cost; diversity and inclusion; equity, diversity, and inclusion; ergonomics; ethnic minority; hazard; improved; innovation; medically underserved; microbiome research; programs; repaired; tumor immunology; undergraduate student; underserved community

ABSTRACT The University of Louisville (UofL) is an Institution of Emerging Excellence (IEE) and one of 23 states designated by the National Institutes of Health (NIH) as an Institutional Development Award (IDeA) state, serving the research needs of medically underserved communities. As part of the IDeA state program, UofL is the recipient of four NIH funded Centers of Biomedical Research Excellence (COBRE) projects to target local and regional health crises in Kentucky and Appalachia. These include centers in 1) Center for Cardiometabolic Science, 2) Microbiomics and Inflammation, 3) Hepatobiology and Toxicology, and 4) Cancer Immunology and Immunotherapy. UofL is also the recipient of NIH funding for the Alcohol Center and the Envirome Institute Superfund Research Center, which studies the effects of cigarette smoke, e- cigarettes and other inhaled toxins on the cardiovascular system. UofL is requesting $306,360.00 for a modern, innovative, eco-friendly tunnel washer in the centrally located A- Tower Research Building Cagewash Facility. The A-Tower is adjacent to six research buildings that comprise the nucleus of the Health Sciences Campus (HSC), and serves as the primary cage wash facility for all rodent species on the HSC and the undergraduate Belknap campus. It also provides essential support for large animal cage washing. The current tunnel washer is over 20 years old, and is not ergonomically or eco-friendly. Routine maintenance and repair are frequent and costly. The Better Built Tunnel Washer, Model T236, represents a major innovative upgrade in cage wash equipment that is eco-friendly, integrative, and utilizes microcomputer technology. The new tunnel washer will increase our current cage wash throughput capacity by 25% for rodent caging and large animal caging accessories, to accommodate our growing rodent and large animal populations. The new cage washer will provide essential support for the four NIH funded COBRE grants, the Envirome Institute Superfund, and 64 investigators in 24 departments across the HSC and Belknap campus. A broad, diverse range of investigators and their research efforts in both biomedical and basic sciences will benefit from this equipment in this shared-use facility. This aligns with the principal missions of the NIH-NIGMS. UofL echoes these missions, with the establishment of the Diversity, Equity and Inclusion Strategic Plan in 2017 and the HSC Office of Diversity and Inclusion, which is committed to expanding funding and employment of ethnic minorities.

摘要 路易斯维尔大学(UofL)是一所新兴卓越学院(IEE)，是23所 被国家卫生研究院(NIH)指定为机构发展的国家 奖励(IDEA)州，服务于医疗服务不足社区的研究需求。作为一部分 在IDEA国家计划中，UofL是NIH资助的四个生物医学中心的接受者 针对肯塔基州当地和地区性健康危机的卓越研究(Cobre)项目 和阿巴拉契亚。这些中心包括1)心脏代谢科学中心，2) 微生物学和炎症，3)肝生物学和毒理学，4)癌症免疫学 和免疫疗法。UofL也是NIH酒精中心和 环境研究所超级基金研究中心，研究吸烟的影响，e- 香烟和其他吸入毒素对心血管系统的影响。UofL正在请求 306,360.00美元，用于中心位置A-的现代化、创新、环保的隧道垫圈 塔式研究大楼Cagewash设施。A塔毗邻六座研究大楼 构成健康科学校园(HSC)的核心，并作为主要的 为HSC和贝尔克纳普本科生校园的所有啮齿动物物种提供笼子清洗设施。它 也为大型动物笼子的清洗提供必要的支持。目前的隧道清洗机是 20岁以上，不符合人体工程学或环保。日常维护和维修包括 频繁且成本高昂。T236型隧道垫圈制造得更好，代表着一项重大创新 升级环保、一体化、采用微电脑的笼式清洗设备 技术新的隧道洗涤机将使我们目前的笼式洗涤能力增加 25%用于鼠笼和大型动物笼配件，以适应我们日益增长的 啮齿动物和大型动物种群。新的笼式垫圈将为 美国国立卫生研究院资助了4名科布雷基金、环境研究所超级基金和的24名调查人员 HSC和贝尔纳普校区的各个部门。广泛、多样的调查人员和 他们在生物医学和基础科学方面的研究工作将在#年受益于这种设备。 这个共享设施。这与NIH-NIGMS的主要任务一致。UofL回波 这些特派团在#年制定了多样性、公平和包容性战略计划 2017和HSC多样性和包容性办公室，该办公室致力于扩大资金 和少数民族就业。