Exercise adherence and cognitive decline: Engaging with the Black community to develop and test a goal-setting and exercise intensity intervention
Exercise adherence and cognitive decline: Engaging with the Black community to develop and test a goal-setting and exercise intensity intervention
批准号:
10767102
负责人:
Angela Bryan
金额:
$37.94万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-09-18 至 2025-08-31
关键词:
AdherenceAdoptedAdultAffectAffectiveAfrican AmericanAfrican American populationAgeAge-associated memory impairmentAgingAllelesAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAmericanAmyloid beta-ProteinApolipoprotein EAreaAwarenessBehaviorBenchmarkingBiologicalBiological MarkersBlack AmericanBlack raceCardiovascular DiseasesChronic DiseaseCodeCollaborationsCommunitiesDataDemographic FactorsDevelopmentDiabetes MellitusDisparityEffectivenessEffectiveness of InterventionsEquityEthnic OriginExerciseFeedbackGenesGeneticGenotypeGoalsGuidelinesHealthHealth behavior and outcomesImmigrantImmigrant communityImpaired cognitionIndividualInterventionIntervention TrialLife StyleLightLiteratureMaintenanceMeasuresMediatingMediatorMeta-AnalysisMethodsModerate ExerciseMorbidity - disease rateNot Hispanic or LatinoOutcomeParticipantPersonsPhasePhysical activityPlasmaPopulationPrevalencePreventionProcessPublic HealthRaceRecommendationReportingResearchResearch DesignRiskSamplingSelf EfficacyStrenuous ExerciseStructural RacismSystemTechniquesTestingTranslatingTreatment EfficacyUnderrepresented PopulationsVascular DementiaVulnerable PopulationsWorkWorld Health Organizationacceptability and feasibilitybehavioral adherencecommunity engaged researchdesigneconomic costefficacy testingexercise adherenceexercise intensityexercise interventionexercise regimenfeasibility trialhealth disparityhuman old age (65+)hyperphosphorylated tauintervention effectintrinsic motivationmeetingsmembermetropolitanmild cognitive impairmentmoderate-to-vigorous physical activitymortalityneglectneurofilamentpeople of colorperson centeredpilot trialpsychologicrandomized trialrecruitresponserisk mitigationsocioeconomicstau Proteinstau-1theoriesvigorous intensity
中文摘要
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英文摘要
Project Summary
The average age of the U.S. population is rapidly increasing and with it the prevalence of age-associated
cognitive decline. Furthermore, the risk for age-associated cognitive decline may disproportionately affect
many historically underrepresented groups. Regular physical activity (PA) is associated with lower risk for
cognitive decline, but many people struggle to maintain PA over the long term. Goal setting presents one
promising avenue to facilitate PA maintenance and has strong public health significance. Likewise, exercise
intensity may further this aim as challenging goals for higher intensity PA may provide the most robust PA
maintenance. Importantly, however, most existing research on goal setting, exercise intensity, and theory-
based exercise interventions overall has been generated among high SES, low diversity samples, and the field
has largely neglected this disparity, with recent reviews and meta-analyses failing to even report racial, ethnic,
or socioeconomic demographic factors. While systems of oppression and structural racism undoubtedly
influence disparities in health behavior and outcomes, it is also possible that existing individual-level theory-
based interventions are not culturally appropriate for many communities, such as African Americans and Black
immigrants (i.e., the Black community). In this application, we will take a community engaged research
approach to tailor and test a theory-based intervention promoting adherence to recommended levels of PA in
the Black community using the technique of person-centered goal setting. We will determine whether
prescriptions of different PA intensities moderate the effectiveness of these goal-setting approaches and test
the theoretical mediators associated with the effectiveness of these interventions on behavioral adherence and
healthy changes in biomarkers associated with cognitive decline. Therefore, the overarching goals of this
project are to take a community engaged research approach to 1) tailor a theory-based goal-setting
exercise intervention in the Denver metropolitan area Black community (R61) and 2) utilize the
Operating Conditions Framework to test the efficacy of the intervention for PA adherence, weekly
volume of exercise, and changes in biomarkers associated with cognitive decline (R33). These
objectives will be met through collaboration with our community partner The Gyedi Project to focus on and fully
engage the Black community in the Denver metropolitan area in the research process.
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海外基金