Biomedical Imaging and Molecular Structural Studies-RCMI

生物医学成像和分子结构研究

• 批准号: 7649684
• 负责人: ROBERT E. TAYLOR
• 金额: $ 106.14万
• 依托单位: HOWARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-09-30 至 2009-09-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7649684
• 关键词: Biomedical; Imaging; Molecular; Structural; Studies

Howard University recognizes that a variety of diseases disproportionately affect disadvantaged minority populations and that the resolution of these diseases will require the systematic involvement of cutting edge biomedical research tools and approaches. This proposal focuses on the enhancement and further development of two research core laboratories, the expansion of which will ensure the University's ability to contribute substantially to studies of those diseases that disproportionately affect disadvantaged populations. These two core laboratories are the Laboratory of Molecular Computations and Bioinformatics (LMCB) and the Biomedical NMR Laboratory (BNMR). The core laboratories are utilized by investigatorinitiated projects. Pilot projects are also proposed that will use the resources provided by the core laboratories. The LMCB will provide resource support to biomedical research projects in the areas of molecular modeling, molecular dynamics, bioinformatics, and quantum chemistry calculations. The BNMR laboratory will provide support to projects involving biomedical imaging and structural NMR investigations. The majority of the projects supported by the BNMR laboratory are cancer related projects. The LMCB provides support to cancer related projects and AIDS related projects. However, both the LMCB and the BNMR laboratory also provide support to projects that are neither cancer nor AIDS related. Attainment of these objectives will contribute to Howard University's goals of addressing diseases which disproportionately affect disadvantaged minority populations.

霍华德大学认识到，各种疾病不成比例地影响弱势群体 这些疾病的解决将需要最先进的系统参与， 生物医学研究工具和方法。本建议的重点是加强和进一步 发展两个研究核心实验室，其扩建将确保大学的能力， 对那些严重影响弱势群体的疾病的研究作出重大贡献 人口。这两个核心实验室是分子计算和生物信息学实验室 （LMCB）和生物医学NMR实验室（BNMR）。核心实验室由发起人 项目还提议开展试点项目，利用核心方案提供的资源， laboratories.生物医学及生物医学统筹局将为以下范畴的生物医学研究项目提供资源支援： 分子建模、分子动力学、生物信息学和量子化学计算。BNMR 实验室将为涉及生物医学成像和结构核磁共振研究的项目提供支持。 BNMR实验室支持的大多数项目都是与癌症相关的项目。关于LMCB 为癌症相关项目和艾滋病相关项目提供支持。然而，LMCB和 BNMR实验室还为与癌症或艾滋病无关的项目提供支持。实现 这些目标将有助于霍华德大学解决疾病的目标， 影响弱势少数群体。