MASS SPECTROMETRIC CHARACTERIZATION OF SULFATED ANTI-HIV ANTIBODIES

硫酸化抗 HIV 抗体的质谱表征

• 批准号: 7562113
• 负责人: Michael R. Farzan
• 金额: $ 5.8万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7562113
• 关键词: Antibodies; Computer Retrieval of Information on Scientific Projects Database; Computer Systems Development; Funding; Grant; HIV-1; In Vitro; Inorganic Sulfates; Institution; Peptides; Recombinant Proteins; Research; Research Personnel; Resources; Role; SIV; Source; Tyrosine; United States National Institutes of Health; Unspecified or Sulfate Ion Sulfates; sulfation; tyrosine O-sulfate

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aims of this R01 grant include assessment of the role of tyrosine sulfation of HIV-1 and SIV coreceptors, development of systems for in vitro sulfation of recombinant proteins, and further characterization of the ability of tyrosine-sulfated peptides to inhibit HIV-1 entry.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该R 01资助的目的包括评估HIV-1和SIV辅助受体酪氨酸硫酸化的作用，开发重组蛋白体外硫酸化系统，以及进一步表征酪氨酸硫酸化肽抑制HIV-1进入的能力。