EFFECT OF RELOCATION ON NIGHTTIME ACTIVITY AND STRESS RESPONSES IN MACAQUES

搬迁对猕猴夜间活动和应激反应的影响

• 批准号: 7562043
• 负责人: MARSHA L DAVENPORT
• 金额: $ 0.54万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7562043
• 关键词: Adrenal Glands; Adult; Animals; Behavior; Behavior assessment; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Hair; Health; Hour; Housing; Human; Hypothalamic structure; Institution; Long-Term Effects; Macaca; Macaca mulatta; Pituitary Gland; Plasma; Research; Research Personnel; Resources; Saliva; Sampling; Self-Injurious Behavior; Source; Stress; Teenagers; United States National Institutes of Health; biological adaptation to stress; male; young adult

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Self-injurious behavior (SIB) is a significant human health problem which is on the rise among teenagers and young adults. A small percentage of normally reared, individually housed adult male rhesus monkeys spontaneously develop self-injurious behavior (SIB). In this subproject, we examined the short- and long-term effects of a relocation stress on behavior and hypothalamic-pituitary-adrenal function in rhesus monkeys with and without SIB. The animals were moved to a new building with different caging and new roommates, changes that were expected to be stressful. Behavioral assessments were conducted during daylight and evening hours, and samples of plasma, saliva, and hair were collected before, shortly after, and 1 year following the move.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 自伤行为（SIB）是一个重要的人类健康问题，在青少年和年轻人中呈上升趋势。一小部分正常饲养、单独圈养的成年雄性恒河猴会自发地产生自伤行为（SIB）。在这个子项目中，我们研究了搬迁压力对有和没有SIB的恒河猴行为和下丘脑-垂体-肾上腺功能的短期和长期影响。这些动物被转移到一个新的建筑物，有不同的笼子和新的室友，这些变化预计会带来压力。在白天和晚上进行行为评估，血浆，唾液和头发的样本收集之前，不久后，和1年后的移动。