Methylation sensitive genes and the transition to allergic disease: a twin study
Methylation sensitive genes and the transition to allergic disease: a twin study
批准号:
nhmrc : 1063394
负责人:
Dr Deborah Strickland
金额:
$32.93万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31
中文摘要
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英文摘要
Australia has amongst the highest reported prevalence allergic conditions (including asthma) in the world. Despite this, little is known about how these conditions arise. Mounting evidence implicates environmentally induced disruption of the genetic blueprint via a process known as epigenetics. We are combining the strengths of a unique collection of identical twins where one of a pair is sensitive to house dust mite, with cutting edge genomics, to characterise the pathways leading to allergy in children.
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Towards reducing the susceptibility of “high risk” infants to allergic asthma by therapeutic modulation of immunoregulatory functions in the pregnant mother.
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批准号:nhmrc : 1047212
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项目类别:Project Grants
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资助金额:$29.72万
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财政年份:2013
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负责人:Dr Deborah Strickland
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依托单位:
Early antecedents of food allergy: defining the pathways underlying very early sensitisation to foods.
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批准号:nhmrc : 1046036
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项目类别:Project Grants
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资助金额:$40.49万
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财政年份:2013
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负责人:Dr Deborah Strickland
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依托单位:
Respiratory viral infections as triggers of acute severe asthma exacerbations in atopics: mechanistic studies in an experimental model
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批准号:nhmrc : 1008741
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项目类别:NHMRC Project Grants
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资助金额:$43.98万
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财政年份:2011
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负责人:Dr Deborah Strickland
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依托单位:
Regulation of T-cell activation in the airway mucosa of rats expressing low versus high IgE responder phenotype
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批准号:nhmrc : 458546
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项目类别:NHMRC Project Grants
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资助金额:$47.55万
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财政年份:2007
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负责人:Dr Deborah Strickland
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依托单位:
Asthma prevention and treatment using UVB radiation-induced immunomodulation
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批准号:nhmrc : 458612
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项目类别:NHMRC Project Grants
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资助金额:$33.1万
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财政年份:2007
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负责人:Dr Deborah Strickland
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依托单位:
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