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Genetic Analysis of Attention Deficit Hyperactivity Disorder

Genetic Analysis of Attention Deficit Hyperactivity Disorder
注意力缺陷多动障碍的遗传分析
批准号：
7594313
负责人：
Maximilian Muenke
金额：
$152.3万
依托单位：
NATIONAL HUMAN GENOME RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7594313
关键词：
AffectAttention deficit hyperactivity disorderBrain DiseasesChildClinicalColombiaDataFamilyGenerationsGenesGeneticGenomeGermanyGoalsHaplotypesHuman GenomeLeadLinkMedicinePersonsPredispositionPrevalenceProcessRecruitment ActivitySchool-Age PopulationSiblingsSouth AmericaTherapeuticbasegenetic analysis

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英文摘要
Attention Deficit Hyperactivity Disorder (ADHD) is a genetically influenced brain disorder with a prevalence of 3-5% in school-age children. Affected sibling pairs and densely affected multi-generation families have been recruited from Colombia, South America, the US, and Germany. A genome-wide search for loci linked to ADHD has been completed and we have identified at least five regions in the human genome that contain genes to may contribute to ADHD (Arcos-Burgos et al. 2004). To date, we have complete clinical information on a total of over 600 small and large, multi-generation families, respectively (Palacio et al., 2004; Jain et al. 2006). We are now in the process to use the clinical and genome data to search for genes that contribute to ADHD
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GENETIC ANALYSIS OF HUMAN BRAIN DEVELOPMENT
  • 批准号：
    2502634
  • 项目类别：
  • 资助金额：
    $39.77万
  • 财政年份：
    1994
  • 负责人：
    Maximilian Muenke
  • 依托单位：
    CHILDREN'S HOSP OF PHILADELPHIA
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