CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: AIDS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 尽管我们对人类疾病的基本机制的理解取得了爆炸性的进展，但有意义的 将这些知识转化为治疗和预防疾病的工作进展缓慢。至 加快基础科学发现服务于我们患者健康的步伐 社区，我们打算在Trip大学建立一个临床和翻译科学研究所(CTSI) 加州大学旧金山分校(UCSF)。它的使命将是创建一个全面、综合的 加州大学旧金山分校促进临床和转化科学研究和教育的学术主页，网址： 在附属机构和参与社区中开展合作。其目标是：(1)支持、增强和 整合现有培训计划，增加来自不同学科和 提高临床和转化性研究方法培训的质量；(2)支持， 改进和集成现有基础设施，以增强临床和 翻译研究，促进合作，实现高质量、原创的不同领域 (3)促进临床和转化型研究人员的职业发展 指导和促进原创研究的机会，并通过改变学术文化来 适当奖励多学科协同工作；(4)1.打造“虚拟家园”，提供 当代通信，简化协作，提供最佳信息学矩阵 进行创新研究，并培育临床和转化科学的发展。 为了实现这些目标，加州大学旧金山分校正在将其临床和翻译研究组织转变为 建立13个相互关联的计划，提供所需的培训、服务和机会。 这些项目由来自加州大学圣迭戈分校四个不同学科的资深科学家领导 健康科学学校？牙科、医学、护理和药学？及其研究生部。这个 计划反映了来自200多名感兴趣、精力充沛和敬业的参与者的意见 整个社区，包括加州大学旧金山分校的大多数学术领袖。这些人曾在 协作确保设计和规划中的包容性、透明度和灵活性 实施CTSI。CTSI愿景的重大财政承诺由 四所学校和总理府。我们相信这一点 注入新的能量和资源，将创造和维持丰富的创新研究环境 并推动实现加州大学旧金山分校的全部潜力，以教育和支持临床和 翻译科学家。如果是这样的话，生物医学将会进步，我们患者和 社区将受益。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Despite explosive gains in our understanding of the basic mechanisms of human disease, meaningful translation of this knowledge to the treatment ahd prevention of disease has moved slowly. To accelerate the pace at which discoveries in basic science can serve the health of our patients and community, we intend to establish a Clinical and Translational Science Institute (CTSI) at trip University of California, San Francisco (UCSF). Its mission will be to create a comprehensive, integrated academic home that.promotes research and education in clinical and translational science at UCSF, at affiliated institutions, and in participating communities. Its goals are: (1) to support, enhance, and integrate existing training programs, increasing the number of trainees from diverse disciplines and improving the quality of their training in clinical and translational research methods; (2) to support, improve, and integrate existing infrastructure to enhance the design and implementation of clinical and translational studies, fostering collaborations to achieve a diverse spectrum of high quality, original research; (3) to enhance career development of clinical and translational researchers by providing mentoring and opportunities to catalyze original research and by changing the academic culture to appropriately reward multidisciplinary collaborative work; (4)1o create a "Virtual Home" providing contemporary communications to simplify collaboration, to provide an optimal informatics matrix for conducting innovative research, and to nurture the growth of clinical and translational science. To reach these goals, UCSF is transforming its clinical and translational research organization to establish 13 interrelated programs that will provide the training, services, and opportunities needed. These programs are led by senior scientists drawn from diverse disciplines in each of UCSPs four health science schools?Dentistry, Medicine, Nursing, and Pharmacy?and its Graduate Division. The plans reflect input from more than 200 interested, energetic, and committed participants from throughout the community, including most of UCSF's academic leaders. These individuals worked collaboratively to ensure inclusion, transparency, and flexibility in the design and planned implementation of the CTSI. A significant financial commitment to the CTSI vision has been provided by the four schools and by the Chancellor's Office. We believe that this infusion of new energy and resources will create and sustain a rich environment for innovative research and drive the realization of UCSF's full potential to educate and to support the work of clinical and translational scientists. If so, biomedicine will be advanced and the health of our patients and the community will benefit.