CTSA INFRASTRUCTURE FOR AIDS RESEARCH
CTSA 艾滋病研究基础设施
基本信息
- 批准号:8365022
- 负责人:
- 金额:$ 237.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-07-01 至 2012-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This subproject represents an estimate of the percentage of the CTSA funding that is
being utilized for a broad area of research (AIDS research, pediatric research, or
clinical trials). The Total Cost listed is only an estimate of the amount of CTSA
infrastructure going towards this area of research, not direct funding provided by
the NCRR grant to the subproject or subproject staff.
DESCRIPTION (provided by applicant): We established the UCSF Clinical and Translational Science Institute (CTSI) at the University of California, San Francisco (UCSF) in 2006 to accelerate the pace of research that improves the health of the public. The overall mission of CTSI has been to improve and transform clinical and translational research infrastructure and training at UCSF and our partner institutions. In the next funding period we aim to use the substantial knowledge, skills, and infrastructure that we have developed to further accelerate the pace of research at UCSF, to export our successes to other institutions, and to create initiatives aimed at improving the health of our own and other communities, through the following aims:
SPECIFIC AIM 1: To enhance the highly successful activities of the UCSF CTSI, including the development of new initiatives in the areas of Training, Infrastructure/Services, and Advocacy/Culture Change: a) Training: to provide programs for students at all levels, across a spectrum of settings, and including all phases of the improvement of healthcare; b) Infrastructure/Services: to expand services and tools to clinical and translational investigators at UCSF, our partner institutions, and within the broader regional, national, and global communities; and, c) Advocacy/Culture Change: to nurture communication, encourage collaboration, foster innovation, and catalyze the successful conduct of clinical and translational research; to support a diverse faculty; to increase involvement of the community and the responsive of research to its needs; and change the academic culture to promote multidisciplinary, collaborative work.
SPECIFIC AIM 2: To develop crosscutting initiatives using the knowledge, skills, and infrastructure developed by multiple CTSI programs in the first funding period to accelerate clinical and translational research and its impact on health, well beyond the institutions collaborating in the UCSF CTSI. New initiatives will: a) Bring together local public health and philanthropic groups to work with CTSI to improve the health of the San Francisco Bay Area community through a series of health improvement projects directed at high impact conditions; b) create a model system to accelerate the pace of clinical and translational research that includes streamlining regulation, developing participant recruitment services, providing research management, and bringing research services directly into community practices; and, c) improve the performance, transparency and accountability of research administration within and beyond CTSI by setting challenging goals and tracking performance metrics on public dashboards.
These aims will be achieved by orchestration of activities occurring within and between our 10 programs, supported by a proven governance model, and with strong ties to institutional and community leadership. Our ultimate goal is to bring better health to more people more quickly.
PUBLIC HEALTH RELEVANCE (provided by applicant): CTSI aims to bring better health to more people more quickly by supporting training, infrastructure, advocacy, and culture change. CTSI achieves this goal not by conducting research but by making it easier for UCSF's superb investigators to conduct research. The current infrastructure and policy environment for clinical and translational research is inefficient, cumbersome and even obstructionist, so CTSI can only meet its goals if it also transforms the way research is done. Its goal is to build innovative infrastructure, tools and services, to transform the core university culture to one which promotes and rewards collaboration and accelerate the clinical application of basic science.
该子项目是对CTSA供资的百分比的估计,
用于广泛的研究领域(艾滋病研究,儿科研究,或
临床试验)。 列出的总成本仅为CTSA金额的估算
基础设施走向这一领域的研究,而不是直接提供资金,
向子项目或子项目工作人员提供NCRR补助金。
描述(由申请人提供):我们于2006年在加州大学弗朗西斯科分校(UCSF)建立了UCSF临床和转化科学研究所(CTSI),以加快改善公众健康的研究步伐。CTSI的总体使命是改善和改造临床和转化研究基础设施,并在UCSF和我们的合作机构培训。在下一个资助期,我们的目标是利用我们开发的大量知识,技能和基础设施,进一步加快UCSF的研究步伐,将我们的成功出口到其他机构,并通过以下目标创建旨在改善我们自己和其他社区健康的举措:
具体目标1:为了提高加州大学旧金山分校CTSI的非常成功的活动,包括在培训,基础设施/服务和宣传/文化变革领域的新举措的发展:a)培训:为各级学生提供课程,跨越一系列设置,包括医疗保健改善的所有阶段; B)基础设施/服务:扩大服务和工具,以临床和翻译研究人员在加州大学旧金山分校,我们的合作伙伴机构,并在更广泛的区域,国家和全球社区;和,c)宣传/文化变革:培养沟通,鼓励合作,促进创新,促进临床和转化研究的成功进行;支持多元化的教师;增加社区的参与和研究的响应其需求;改变学术文化,促进多学科的合作。
具体目标2:利用多个CTSI项目在第一个资助期内开发的知识,技能和基础设施来开发跨领域计划,以加速临床和转化研究及其对健康的影响,远远超出UCSF CTSI合作的机构。新举措将:a)召集当地公共卫生和慈善团体与CTSI合作,通过一系列针对高影响条件的健康改善项目,改善旧金山弗朗西斯科湾区社区的健康; B)创建一个模型系统,以加快临床和转化研究的步伐,包括简化监管,开发参与者招募服务,提供研究管理,并将研究服务直接纳入社区实践; c)通过设定具有挑战性的目标和在公共仪表板上跟踪绩效指标,提高CTSI内外研究管理的绩效、透明度和问责制。
这些目标将通过协调我们10个项目内部和之间的活动来实现,得到经过验证的治理模式的支持,并与机构和社区领导层建立密切联系。我们的最终目标是更快地为更多人带来更好的健康。
公共卫生相关性(由申请人提供):CTSI旨在通过支持培训、基础设施、宣传和文化变革,更快地为更多人带来更好的健康。CTSI实现这一目标不是通过进行研究,而是通过使UCSF的优秀调查人员更容易进行研究。目前临床和转化研究的基础设施和政策环境效率低下,繁琐,甚至是阻碍,因此CTSI只有改变研究方式才能实现其目标。其目标是建立创新的基础设施,工具和服务,将核心大学文化转变为促进和奖励合作的文化,并加速基础科学的临床应用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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S. CLAIBORNE JOHNSTON其他文献
S. CLAIBORNE JOHNSTON的其他文献
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{{ truncateString('S. CLAIBORNE JOHNSTON', 18)}}的其他基金
A New CTSA Partnership to Translate an Oral Cancer Biomarker from Lab to Clinic
CTSA 建立新合作伙伴关系,将口腔癌生物标志物从实验室转化为临床
- 批准号:
8291650 - 财政年份:2012
- 资助金额:
$ 237.83万 - 项目类别:
CTSA INFRASTRUCTURE FOR PEDIATRIC CLINICAL TRIALS
用于儿科临床试验的 CTSA 基础设施
- 批准号:
8365021 - 财政年份:2011
- 资助金额:
$ 237.83万 - 项目类别:
CTSA INFRASTRUCTURE FOR CLINICAL TRIALS AND PEDIATRIC RESEARCH
CTSA 临床试验和儿科研究基础设施
- 批准号:
8173870 - 财政年份:2010
- 资助金额:
$ 237.83万 - 项目类别:
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