CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 尽管我们对人类疾病的基本机制的理解取得了爆炸性的进展， 将这些知识转化为疾病的治疗和预防进展缓慢。到 加快基础科学发现为患者健康服务的步伐， 我们打算在特里普大学建立一个临床和转化科学研究所（CTSI） 位于加州的旧金山弗朗西斯科（UCSF）。它的使命将是建立一个全面、综合的 学术之家。促进临床和转化科学的研究和教育在加州大学旧金山分校，在 附属机构和参与社区。它的目标是：（1）支持，加强， 整合现有的培训计划，增加来自不同学科的学员人数， 提高他们在临床和转化研究方法方面的培训质量;（2）支持， 改善和整合现有基础设施，以加强临床和 转化研究，促进合作以实现多样化的高质量、原创性 （3）通过提供以下服务，促进临床和转化研究人员的职业发展 指导和机会，以促进原创性研究，并通过改变学术文化， 适当奖励多学科协作工作;（4）1 o创建一个“虚拟家园”， 现代通信，以简化协作，提供最佳的信息矩阵， 开展创新研究，并促进临床和转化科学的发展。 为了实现这些目标，UCSF正在转变其临床和转化研究组织， 建立13个相互关联的方案，提供所需的培训、服务和机会。 这些项目由来自UCSP四个不同学科的高级科学家领导。 健康科学学校？牙科、医学、护理和药学？及其研究生部。的 计划反映了来自200多个感兴趣的，充满活力的和坚定的参与者的意见， 整个社区，包括大多数UCSF的学术领袖。这些人工作 协作，以确保设计和规划中的包容性，透明度和灵活性 实施CTSI。对CTSI愿景的重大财政承诺来自 四所学校和校长办公室。我们认为这 新能源和新资源的注入将为创新研究创造和维持一个丰富的环境 并推动实现UCSF的全部潜力，以教育和支持临床和 翻译科学家如果是这样的话，生物医学将是先进的，我们的病人和病人的健康将得到改善。 社区将受益。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Despite explosive gains in our understanding of the basic mechanisms of human disease, meaningful translation of this knowledge to the treatment ahd prevention of disease has moved slowly. To accelerate the pace at which discoveries in basic science can serve the health of our patients and community, we intend to establish a Clinical and Translational Science Institute (CTSI) at trip University of California, San Francisco (UCSF). Its mission will be to create a comprehensive, integrated academic home that.promotes research and education in clinical and translational science at UCSF, at affiliated institutions, and in participating communities. Its goals are: (1) to support, enhance, and integrate existing training programs, increasing the number of trainees from diverse disciplines and improving the quality of their training in clinical and translational research methods; (2) to support, improve, and integrate existing infrastructure to enhance the design and implementation of clinical and translational studies, fostering collaborations to achieve a diverse spectrum of high quality, original research; (3) to enhance career development of clinical and translational researchers by providing mentoring and opportunities to catalyze original research and by changing the academic culture to appropriately reward multidisciplinary collaborative work; (4)1o create a "Virtual Home" providing contemporary communications to simplify collaboration, to provide an optimal informatics matrix for conducting innovative research, and to nurture the growth of clinical and translational science. To reach these goals, UCSF is transforming its clinical and translational research organization to establish 13 interrelated programs that will provide the training, services, and opportunities needed. These programs are led by senior scientists drawn from diverse disciplines in each of UCSPs four health science schools?Dentistry, Medicine, Nursing, and Pharmacy?and its Graduate Division. The plans reflect input from more than 200 interested, energetic, and committed participants from throughout the community, including most of UCSF's academic leaders. These individuals worked collaboratively to ensure inclusion, transparency, and flexibility in the design and planned implementation of the CTSI. A significant financial commitment to the CTSI vision has been provided by the four schools and by the Chancellor's Office. We believe that this infusion of new energy and resources will create and sustain a rich environment for innovative research and drive the realization of UCSF's full potential to educate and to support the work of clinical and translational scientists. If so, biomedicine will be advanced and the health of our patients and the community will benefit.