MicroRNA expression profiling of eutopic endometrium in women with versus without endometriosis

子宫内膜异位症女性与非子宫内膜异位症女性在位子宫内膜的 MicroRNA 表达谱

• 批准号: nhmrc : 1052866
• 负责人: Dr Zhao Wang
• 金额: $ 14.95万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/microrna-expression-profiling-versus-endometriosis/112300
• 关键词: MicroRNA; expression; profiling; eutopic; endometrium

Endometriosis is a medical condition where endometrium grows outside the womb. About 10% of women have this condition that can cause abdominal pain, painful periods and difficulty conceiving a child. Now endometriosis can only be diagnosed by surgical procedure. We believe that the presence of endometriosis causes particular small molecules called microRNAs to be present in the lining of the womb or in the blood only in women with endometriosis, and we could develop a test for endometriosis without resorting to surgery.

子宫内膜异位症是子宫内膜在子宫外生长的一种疾病。大约 10% 的女性患有这种疾病，会导致腹痛、经痛和怀孕困难。现在子宫内膜异位症只能通过手术来诊断。我们相信，子宫内膜异位症的存在会导致称为 microRNA 的特殊小分子仅存在于患有子宫内膜异位症的女性的子宫内膜或血液中，并且我们可以开发一种无需手术的子宫内膜异位症检测方法。