Alcohol Biomarkers in General Clinical Settings

一般临床环境中的酒精生物标志物

基本信息

批准号：
7682257
负责人：
MICHAEL F. FLEMING
金额：
$ 14.31万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-20 至 2010-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7682257
关键词：
Acute Address Admission activity Adult Alcohol dependence Alcohol withdrawal syndrome Alcoholic beverage heavy drinker Alcohols Area Attention deficit hyperactivity disorder Australia Award Biological Markers Caring Child Clinical Clinical Research Commit Complement Consult Consultations Data Databases Development Doctor of Philosophy Early identification Economics Elective Surgical Procedures Europe FDA approved Fetal Alcohol Spectrum Disorder Frequencies Funding Germany Goals Grant Guidelines Healthcare Hospital Costs Hospitals Inpatients Intensive Care Units Leadership Length of Stay Mechanical Ventilators Medicine Mentors Methods Mid-Career Clinical Scientist Award (K24)National Institute on Alcohol Abuse and Alcoholism Nosocomial Infections Operative Surgical Procedures Patient Care Patients Persons Pharmaceutical Preparations Physicians Policy Maker Property Psychometrics Registries Research Research Methodology Research Personnel Respiratory Failure Risk Sampling Schedule Schools Scientist Sensitivity and Specificity Services Severities Students Surgeon Testing Time Training Training Programs Translational Research Trauma United States National Institutes of Health University Hospitals Wisconsin Work addiction alcohol related problem alcohol research alcohol risk base career cost design diabetic falls follow-up graduate student interest patient oriented patient oriented research prevent programs research study tool

项目摘要

DESCRIPTION (provided by applicant): Background: Dr. Fleming has spent the majority of the last 15 years conducting alcohol research, mentoring alcohol researchers, caring for patients and providing consultation to physicians and health care leaders. The PI is committed to continuing his work in the area of patient-oriented research, mentoring, leadership and patient care for the remainder of his academic career. Dr. Fleming is committed to addressing the critical shortage of physician scientists conducting research in the alcohol area. Goal of K24 application: The goal of this application is to provide the PI with 25% time to mentor junior patient oriented investigators and develop new graduate school courses in clinical research as well as an additional 25% time to expand his research program into the areas of alcohol biomarkers, alcohol-related trauma and medication treatment of children with ADHD and fetal alcohol spectrum disorder. If the K24 is awarded in July 2005, he would be funded 40% time on two NIAAA funded R01 grants (R01AA012522-03 and R01AA014685-01), 10% time by his department for his clinical work and 50% time by the proposed K24 grant. Dr. Fleming is completing follow up work on three NIH grants that were completed in the fall of 2004 (R21AA013368-02, R01DA013686-02 and R01AA12664-01A2). Proposed mentoring activities: The K24 award will allow him to expand his research mentoring activities in the alcohol area to include new research fellows and graduate students. It would allow him to spend more time on his recently awarded new NIAAA T32 grant which will fund three physician scientists per year. This training program will focus on increasing the number of physicians who conduct NIAAA funded research. He plans to develop 1-2 new graduate school courses on how to conduct alcohol research with a focus on research methodology and analysis strategies. Significance: The proposed K24 complements the current NIH Roadmap Initiatives. The grant will facilitate Dr. Fleming's ability to train new physician scientists, develop graduate-level courses for masters and PhD students interested in clinical research as well as increasing his capacity to conduct translational research.

描述（由申请人提供）：背景：弗莱明博士在过去的15年中的大部分进行酒精研究，指导酒精研究人员，照顾患者并向医师和卫生保健领导者提供咨询。 PI致力于在其剩余的学术生涯中继续在以患者为导向的研究，指导，领导和患者护理领域继续工作。弗莱明博士致力于解决在酒精区进行研究的医师科学家的严重短缺。 K24应用的目标：本应用的目的是为PI提供25％的时间，以指导初级患者以患者为导向的研究人员，并在临床研究中开发了新的研究生院课程，以及额外的25％时间，将其研究计划扩展到酒精生物标记物，与酒精相关的创伤和药物治疗的ADHD和胎儿酒精饮酒症治疗。如果K24于2005年7月授予K24，则他将获得40％的时间，两次NIAAA资助的R01赠款（R01AA012522-03和R01AA014685-01），其临床工作部门为10％的时间和10％的时间，由提议的K24 Grant获得50％的时间。 Fleming博士正在完成2004年秋季完成的三项NIH赠款的后续工作（R21AA013368-02，R01DA013686-02和R01AA12664-01A2）。拟议的指导活动：K24奖将使他能够在酒精区扩大研究指导活动，包括新的研究研究员和研究生。这将使他能够在最近授予的新NIAAA T32赠款上花费更多时间，该拨款将为每年提供三名医师科学家。该培训计划将着重于增加进行NIAAA资助研究的医师数量。他计划开发有关如何以研究方法和分析策略为重点进行酒精研究的1-2个新的研究生课程。意义：拟议的K24补充了当前的NIH路线图计划。该赠款将促进弗莱明博士培训新医师科学家的能力，为对临床研究感兴趣的硕士和博士生开发研究生级课程，并提高其进行转化研究的能力。