A5164: A PHASE IV STUDY OF ANTIRETROVIRAL THERAPY FOR HIV-INFECTED ADULTS

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这是一项在未接受过抗逆转录病毒治疗（或远程最小治疗）的晚期免疫缺陷综合征受试者中进行的立即与延迟抗逆转录病毒治疗的随机IV期研究，这些受试者表现为急性艾滋病相关机会性感染（OI）或细菌性肺炎，CD 4+计数< 200个细胞/mm 3，且有公认的有效抗菌治疗。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a randomized Phase IV study of immediate versus deferred antiretroviral therapy in antiretroviral-naive subjects (or distant minimal treatment) with advanced immunodeficiency syndrome who are presenting with acute AIDS-related opportunistic infection (OIs) or bacterial pneumonia and CD4+ count < 200 cells/mm3 for which there are recognized effective antimicrobial therapies available.