Migratory cells to ganglionated network: self-organization of the enteric nervous system

细胞向神经节网络的迁移：肠神经系统的自组织

• 批准号: nhmrc : 607379
• 负责人: Dr Donald Newgreen
• 金额: $ 21.89万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/migratory-cells-ganglionated-enteric-nervous/76741
• 关键词: Migratory; cells; ganglionated; network; self

The intestine has its own nervous system. This develops from cells that wander into the intestine during early development and self-organize to form the functional nervous system . The correct organization of the cells of this nervous system is required for correct intestine function. How they self-organize is not known, and there are diseases in which the process is disturbed. Molecular and cell biology and mathematical modelling will be used to understand how this occurs.

肠道有自己的神经系统。这是从早期发育过程中进入肠道的细胞发展而来，并自我组织形成功能性神经系统。这种神经系统的细胞的正确组织是正确的肠道功能所必需的。它们是如何自我组织的尚不清楚，有些疾病的这一过程受到干扰。分子和细胞生物学以及数学建模将用于了解这是如何发生的。