GENETIC EPIDEMIOLOGY OF ENERGY METABOLISM

能量代谢的遗传流行病学

• 批准号: 7607724
• 负责人: Stephen R Daniels
• 金额: $ 0.95万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-15 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607724
• 关键词: 16 year old; Adolescence; African American; Blood; Body Composition; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Development; Dual-Energy X-Ray Absorptiometry; Energy Metabolism; Funding; Genes; Genotype; Grant; Height; Institution; Measurement; Medical center; Obesity; Pediatric Hospitals; Purpose; Research; Research Personnel; Resources; Rest; Scanning; Source; Testing; United States National Institutes of Health; Visit; Weight; genetic epidemiology; girls; interest; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to better understand how genes may influence resting energy expenditure in 12  16 year old African American girls which may contribute to the development of obesity during adolescence. There are two parts to the study. Initially, we will buccal screen 1000 girls for genotyping. Those that are a match the specific genes we are interested in, will be asked to come for an overnight visit at Cincinnati Children's Hospital Medical Center's General Clinical Research Center. At the overnight visit, the subject will have measurements of body composition such as height, weight and skinfolds. The subject will also have a DXA scan, blood draw, and a Resting Energy test.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是为了更好地了解基因如何影响12岁以下儿童的静息能量消耗。  16岁的非洲裔美国女孩，这可能有助于在青春期肥胖的发展。 本研究分为两个部分。 最初，我们将对1000名女孩进行口腔筛查以进行基因分型。 那些与我们感兴趣的特定基因相匹配的人，将被要求在辛辛那提儿童医院医学中心的综合临床研究中心进行一次通宵访问。 在过夜访视时，受试者将测量身体组成，如身高、体重和皮褶。 受试者还将接受DXA扫描、抽血和静息能量测试。