GH AND INSULIN RESISTANCE IN CHILDREN WITH IUGR

IUGR 儿童的 GH 和胰岛素抵抗

• 批准号: 7607067
• 负责人: Lynne L. Levitsky
• 金额: $ 0.06万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607067
• 关键词: Body Composition; Child; Computer Retrieval of Information on Scientific Projects Database; Effectiveness; Fatty acid glycerol esters; Fetal Growth Retardation; Funding; Grant; Institution; Insulin Resistance; Lead; Low Birth Weight Infant; Magnetic Resonance Imaging; Measures; Muscle; Research; Research Personnel; Resources; Safety; Somatotropin; Source; United States National Institutes of Health; hormone therapy; insulin sensitivity

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Insulin resistance (IR) is associated with special stores of fat in muscle which can be measured by MRI. Growth hormone (GH) treatment can also cause IR. In this study, the effect of GH on muscle fat stores will be examined in children who are short due to low birthweight before and after receiving GH therapy. Assessments include MRI analysis of muscle fat, insulin sensitivity, and body composition. Our studies are intended to determine how GH causes IR and may lead to ways to increase its safety and effectiveness.

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