DOPAMINERGIC FUNCTION IN YOUNG CANNABIS ABUSERS

年轻大麻滥用者的多巴胺能功能

• 批准号: 7608259
• 负责人: SERGE SEVY
• 金额: $ 1.03万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608259
• 关键词: 21 year old; Adolescence; Adult; Age; Cannabis; Computer Retrieval of Information on Scientific Projects Database; Dopamine D2 Receptor; Exploratory/Developmental Grant; Funding; Glucose; Grant; Institution; Measures; Positron-Emission Tomography; Raclopride; Recording of previous events; Rehabilitation therapy; Research; Research Personnel; Resources; Source; United States National Institutes of Health; concept; glucose metabolism; programs; sex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The study proposed in this R21 exploratory/developmental grant will compare fifteen 18-21 year old subjects with a history of prolonged cannabis exposure in adolescence (duration of cannabis use must be more than one year before age 18) and admitted to a residential rehabilitation program (Aurora Concept, Incorporated), with fifteen age- and sex-matched healthy subjects. Regional glucose metabolism (assessed with 18-fluoro-2-deoxy-glucose positron emission tomography (FDG PET) and dopamine D2 receptor availability (assessed with [11C]-raclopride and PET) will be measured.

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