CORE A: ADMINISTRATIVE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 行政核心(核心A)：目标是就调查范围和重点提供建议；招募、指导和促进受训人员；管理和有效利用所有资源；促进与其他科布雷、州和国家项目的富有成效的互动。我们的内部咨询委员会已得到加强，现在包括奥尔特博士、希梅尔法布博士、弗里塞尔博士、威尔第博士、诺尔斯博士、廖中生博士、林德纳博士和普鲁多夫斯基博士。对于受训者，这提供了以下指导关系：Wang Prudovsky&Wojchowski；Yoon，Frisel&Lindner；Oxburgh，Himmelfarb&Wojchowski；De Vries，Knowles&Ault；Mills，Frisel，Ault&Knowles。IAC和实习生务虚会分别于9/06和11/06举行。受训者陈述了结果和目标，并完成了与导师的会议。我们的外部咨询委员会已得到加强，包括N.Spek(达特茅斯大学)、T.Gridley(杰克逊实验室)、P.Besmer(斯隆·凯特林)、G.Sprangrude(犹他州大学)和H.Broxmeyer(印第安纳大学)。L.Zon博士(HMS)也加入了我们的科学咨询委员会。值得注意的是，2006年10月举行了一次非常成功的包罗万象的静修。后续的重点是科学和我们竞争的续签申请定于2007年6月15日举行。CORE A Resources还共同赞助了一系列杰出的研讨会：Frank Costantini(哥伦比亚大学)、Erwin Bottinger(Mt.西奈医学中心)、Tom Gridley(杰克逊实验室)、Vicki Rosen(哈佛大学牙科医学院)、Cathy Mendelsohn(哥伦比亚大学医学中心)、Jordan Kreidberg(马萨诸塞州波士顿儿童医院)和James Palis(罗切斯特大学)。DM Wojchowski博士将继续在制定这一计划方面发挥主导作用。乔·威尔第也将贡献3.6卡。总体而言，Core A旨在(通过高级专家和国家投入)实现以下任务：1/以临床相关的方式科学地推进我们的领域；2/作为有竞争力的独立研究人员推进受训人员；以及3/建立一个国家认可的干细胞生物学和再生医学研究中心。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Administrative Core (Core A): Goals are to advise on investigatory scope and focus; to recruit, mentor and advance trainees; to manage and effectively utilize all resources; and to facilitate productive interactions with other COBRE, State, and National programs. Our Internal Advisory Committee has been bolstered to now include Drs. Ault, Himmelfarb, Friesel, Verdi, Knowles, Liaw, Lindner and Prudovsky. For trainees, this provides the following mentoring relationships: Wang, Prudovsky & Wojchowski; Yoon, Friesel & Lindner; Oxburgh, Himmelfarb & Wojchowski; de Vries, Knowles & Ault; Mills, Friesel, Ault, & Knowles. IAC and trainee retreats were held 9/06 and 11/06. Trainees presented findings and goals, and meeting with mentors were completed. Our External Advisory Committee has been fortified to include N.Speck (Dartmouth), T.Gridley (The Jackson Laboratory), P.Besmer (Sloan Kettering), G.Sprangrude (U Utah), and H.Broxmeyer (Indiana U). Dr L.Zon (HMS) also has joined our Scientific Advisory Board. Notably, a highly successful all-inclusive retreat has held in October, 2006. A follow up that focuses on science and our competing renewal application is scheduled for June 15, 2007. Core A resources also co-sponsor an outstanding seminar series: Frank Costantini (Columbia University), Erwin Bottinger (Mt. Sinai Medical Center), Tom Gridley (The Jackson Laboratory), Vicki Rosen (Harvard School of Dental Medicine), Cathy Mendelsohn (Columbia University Medical Center), Jordan Kreidberg (Children's Hospital, Boston, MA), and James Palis (University of Rochester). Dr. DM Wojchowski will continue to take a lead role in developing this program. Joe Verdi also will contribute 3.6 cal. months effort to Core A. Overall, Core A aims to enable (via expert senior and national input) the tasks of: 1/ scientifically advancing our field (in clinically relevant ways); 2/ advancing trainees as competitive independent investigators; and 3/ establishing a nationally recognized research Center in Stem Cell Biology and Regenerative Medicine.