CORE A: ADMINISTRATIVE

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Goals of Administrative Core (Core A) are to advise on investigatory scope and focus; to recruit, mentor and advance trainees; to manage and effectively utilize all resources; and to facilitate productive interactions with other COBRE, State, and National programs. Our Internal Advisory Committee has been bolstered to include Drs. Ault, Himmelfarb, Friesel, Verdi, Knowles, Lindner and Prudovsky. For trainees, this provides the following mentoring relationships: Wang, Prudovsky & Wojchowski; Yoon, Friesel & Lindner; Oxburgh, Himmelfarb & Wojchowski; de Vries, Knowles & Ault; Mills, Friesel, Ault, & Knowles. IAC and trainee retreats were held 7/05, 11/05, and 3/06. Trainees presented findings and goals, and meeting with mentors were completed. Our External Advisory Committee has been fortified to include N.Speck (Dartmouth), P.Besmer (Sloan Kettering), G.Sprangrude (U Utah), and H.Broxmeyer (Indiana U). Dr L.Zon (HMS) also has joined our Scientific Advisory Board. An all-inclusive retreat is scheduled annually for early Fall. Core A resources (together with parallel Institute dollars) sponsor an excellent seminar series. [G.Dressler (U Michigan), E.Bottinger (Mt Sinai), T.Tenzen (Harvard), W.Wu (Dan-Farber), T.Gridley (Jackson Lab), V.Rosen (Harvard), C.Mendelsohn (Columbia), J.Bonaventre (Brigham &Women's), J.Kreidberg (Children's Hospital), D.Scadden (MGH)]. Dr. DM Wojchowski will continue to take a lead role in developing this program. Joe Verdi also will contribute 30% effort to Core A. Overall, Core A aims to enable (via expert senior and national input) the tasks of: 1/ scientifically advancing our field (in clinically relevant ways); and 2/ advancing trainees as competitive independent investigators.