ADMINISTRATION LEADERSHIP & BIOSTATISTICS CORE

行政领导

• 批准号: 7436690
• 负责人: JOHN Arthur FAULKNER
• 金额: $ 16.22万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7436690
• 关键词: Achievement; Address; Administrative Personnel; Advisory Committees; Age; Aging; Aging-Related Process; Basic Science; Behavior Therapy; Biometry; Biostatistics Core; Communication; Condition; Consultations; Coupled; Data; Documentation; Elderly; Failure to Thrive; Goals; Housing; Institutes; Leadership; Medical; Michigan; Molecular; Numbers; Operative Surgical Procedures; Physiology; Population; Program Research Project Grants; Public Health; Research; Role; Services; Strategic Planning; Structure; Time; Today; Transgenic Animals; Universities; Work; base; cost; day; frailty; medical schools; programs; research and development

The Administrative/Leadership & Biostatistics Core of the Program Project (PPG) exists entirely to support the work of the Projects and Transgenic Animal Core. The Administrative/Leadership & Biostatistics Core is dedicated to the following Specific Aims: 1. Stimulate and facilitate strategic planning, scientific activities, and interactions among the projects and core; 2. Interact with administrative personnel of the University of Michigan (UM) Department of Molecular & Integrative Physiology, the DM Division of Research Development and Administration, and administrative personnel for each project and core to address financial and regulatory issues associated with the successful execution of scientific goals; 3. Maintain communication with and provide necessary documentation of activities to the National Institute on Aging; 4. Facilitate data sharing among the three Projects and acquisition of statistical support; and 5. Organize, co-ordinate, and chair meetings of the Scientific Advisory Committee. The Core is housed physically in the newly opened Basic Science Research Building and resides administratively in the Department of Physiology in the School of Medicine. Thus, a major activity of the Administrative/Leadership component involves integrating the roles of Project Director, John Faulkner; Associate Project Director, Susan Brooks; and Administrative Associate, Jane Heibel with the administrative structure of the Physiology Department. This Core group handles day-today administrative and financial operations of the PPG. Final administrative and scientific responsibility for the PPG resides with the Project Director, in consultation with the Associate Project Director as well as considerable input from each Project Leader. The Biostatistics Unit is directed by Lisa Larkin in consultation with Andrzej Galecki. This Unit provides statistical support to all projects and facilitates data sharing among projects. The relevance to public health of the PPG lies in its focus on the major public health problem of 'frailty and failure to thrive' among the elderly, estimated to currently cost $90 billion per year in the U.S. with a doubling time of 40 years, as both the elderly population and the number of frail people among the elderly increase. Geriatricians cite a lack of understanding of mechanisms underlying frailty as a major factor contributing to the lack of progress in the treatment of the condition. With a focus on understanding the mechanisms underlying the aging-associated changes that result in physical frailty, this PPG has the potential to determine and distinguish the factors underlying the condition that constitute changes intimately coupled to the aging process itself from those that are preventable or treatable by scientifically-based medical or behavioral interventions or public health programs.

该计划项目（PPG）的行政/领导力与生物统计学核心完全存在于 项目和转基因动物核心的工作。行政/领导力和生物统计学核心是 致力于以下具体目的：1。刺激和促进战略计划，科学活动和 项目和核心之间的互动； 2。与大学的行政人员互动 密歇根州（UM）分子与综合生理系DM研究开发部 和管理人员以及每个项目和核心的行政人员，以解决财务问题 与成功执行科学目标相关的监管问题； 3。保持沟通 并向国家老龄研究所提供并提供必要的活动文件； 4。促进数据 在这三个项目中共享并获得统计支持；和5。组织，协调和 科学咨询委员会的主席会议。核心在新近打开的物理上容纳 基础科学研究大楼并在学校的生理系行政上居住 医学。因此，行政/领导力部分的主要活动涉及整合角色 项目总监约翰·福克纳（John Faulkner）；苏珊·布鲁克斯（Susan Brooks）副项目主任；和行政助理， 简·海贝尔（Jane Heibel）与生理部门的行政结构。这个核心团体处理日期 PPG的行政和财务运营。最终的行政和科学责任 PPG与项目总监一起与副项目主任协商以及 每个项目负责人的大量投入。生物统计局由丽莎·拉金（Lisa Larkin）指导 与Andrzej Galecki。该单元为所有项目提供统计支持，并促进数据共享 项目。与PPG公共卫生的相关性在于它的重点是 老年人中的“脆弱和不蓬勃发展”，估计目前在美国每年耗资900亿美元 随着老年人口和老年人的数量，两倍的时间为40年 增加。老年医生认为缺乏对脆弱机制的理解是主要因素 导致病情治疗方面缺乏进展。专注于理解 衰老相关变化的机制导致身体虚弱，该PPG具有 确定和区分构成构成构成的条件的因素的潜力密切变化 与基于科学的基于科学的方法相结合的衰老过程本身可以预防或可以治疗 医疗或行为干预或公共卫生计划。