COMMISSIONING OF BL12-2 ? A NEW HIGH-BRIGHTNESS MACROMOLECULAR CRYSTALLOGRAPHY B

BL12-2 的调试？

• 批准号: 7598174
• 负责人: THOMAS RABEDEAU
• 金额: $ 8.93万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7598174
• 关键词: Arts; California; Collaborations; Complex; Computer Retrieval of Information on Scientific Projects Database; Crystallography; Foundations; Funding; Gifts; Grant; Hybrids; Institutes; Institution; KLK3 gene; Membrane; Optics; Research; Research Personnel; Resources; Source; System; Technology; United States National Institutes of Health; Vacuum; base; design

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Beam Line 12-2 is a new, in-vacuum undulator based, high-brightness, state-of-the-art macromolecular crystallography beam line that will be particularly optimized for the study of microcrystals, weakly diffracting systems such as membranes and large complexes, and for other demanding scientific projects. It will provide 60% general user access. The beam line was funded by a gift from the Gordon and Betty Moore Foundation in a collaboration between the California Institute of Technology and SSRL. It makes use of a powerful in-vacuum hybrid undulator source. This 67-period undulator was designed so that a 6.0 mm minimum gap operating on SPEAR3 produces a brightness of ~1018 p/s/mrad2/mm2/0.1%bp at an energy of 12 keV, approaching that of the APS UA undulator. Beam was first delivered on November 28, 2006. Subsequently, the undulator and optics were studied and optimization is currently underway.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 光束线12-2是一种新型的、基于真空波荡器的、高亮度的、最先进的大分子晶体学光束线，它将特别优化用于微晶、弱衍射系统（如膜和大型复合物）的研究，以及其他要求苛刻的科学项目。 它将提供60%的一般用户访问。 光束线是由戈登和贝蒂摩尔基金会在加州理工学院和SSRL之间的合作捐赠资助的。 它利用了一个强大的真空混合波荡器源。 该67周期波荡器的设计使得在SPEAR 3上运行的6.0 mm最小间隙在12 keV的能量下产生约1018 p/s/mrad 2/mm 2/0.1%bp的亮度，接近APS UA波荡器的亮度。 Beam于2006年11月28日首次交付。 随后，对波荡器和光学器件进行了研究，目前正在进行优化。