PHYSIOLOGICAL BENEFITS OF MICROBIAL MN OXIDATION

微生物氧化锰的生理益处

• 批准号: 7601064
• 负责人: Bradley M. Tebo
• 金额: $ 1.09万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601064
• 关键词: Bacteria; Bacterial Physiology; Bacteriophages; Computer Retrieval of Information on Scientific Projects Database; Desiccation; Disruption; Funding; Glycocalyx; Grant; Infection; Institution; Light; Mechanics; Mediating; Metals; Oxides; Phylogenetic Analysis; Physiological; Play; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; microbial; oxidation; protective effect; terminally differentiated effector memory (TEM) T cells

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Mn oxides play an important role in the cycling of metals and organics, and bacterially mediated Mn oxidation is largely the source of these reactive Mn oxides. Many different phylogenetic and physiological types of bacteria have been demonstrated to oxidize Mn, yet the benefit or role these oxides play in bacterial physiology has not been determined. We are investigating the protective effects of Mn oxides to UV light, dessication, mechanical disruption, and phage infection. We would like to show that the Mn oxides produced by the bacteria physically coat the cell by TEM.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 锰氧化物在金属和有机物的循环中起着重要作用，细菌介导的锰氧化主要是这些活性锰氧化物的来源。许多不同的系统发育和生理类型的细菌已被证明氧化锰，但这些氧化物在细菌生理学中发挥的作用或益处尚未确定。我们正在研究锰氧化物对紫外线、干燥、机械破碎和噬菌体感染的保护作用。我们想通过TEM显示细菌产生的锰氧化物物理包覆细胞。