PHYSIOLOGICAL BENEFITS OF MICROBIAL MN OXIDATION

微生物氧化锰的生理益处

• 批准号: 7601064
• 负责人: Bradley M. Tebo
• 金额: $ 1.09万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601064
• 关键词: Bacteria; Bacterial Physiology; Bacteriophages; Computer Retrieval of Information on Scientific Projects Database; Desiccation; Disruption; Funding; Glycocalyx; Grant; Infection; Institution; Light; Mechanics; Mediating; Metals; Oxides; Phylogenetic Analysis; Physiological; Play; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; microbial; oxidation; protective effect; terminally differentiated effector memory (TEM) T cells

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Mn oxides play an important role in the cycling of metals and organics, and bacterially mediated Mn oxidation is largely the source of these reactive Mn oxides. Many different phylogenetic and physiological types of bacteria have been demonstrated to oxidize Mn, yet the benefit or role these oxides play in bacterial physiology has not been determined. We are investigating the protective effects of Mn oxides to UV light, dessication, mechanical disruption, and phage infection. We would like to show that the Mn oxides produced by the bacteria physically coat the cell by TEM.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 Mn氧化物在金属和有机物的循环中起重要作用，细菌介导的Mn氧化在很大程度上是这些反应性MN氧化物的来源。已经证明了许多不同的系统发育和生理类型的细菌可以氧化Mn，但是尚未确定这些氧化物在细菌生理学中所起的好处或作用。我们正在研究Mn氧化物对紫外线，涂抹，机械破坏和噬菌体感染的保护作用。我们想证明，细菌产生的Mn氧化物通过TEM物理覆盖细胞。