MULTISCALE MODELS FOR PACKAGING VIRAL DNA

用于包装病毒 DNA 的多尺度模型

• 批准号: 7602256
• 负责人: STEPHEN C. HARVEY
• 金额: $ 0.53万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602256
• 关键词: Capsid; Cereals; Computer Retrieval of Information on Scientific Projects Database; DNA; DNA Packaging; Funding; Goals; Grant; Institution; Kinetics; Modeling; Research; Research Personnel; Resources; Source; Thermodynamics; United States National Institutes of Health; Viral; Viral Packaging; multi-scale modeling

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Using coarse-grained representations of DNA, models of DNA packaged in viral capsids are developed. The overall goal of this project is to provide an understanding of the structural, kinetic and thermodynamic aspects of DNA packaging into viral capsids.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 使用 DNA 的粗粒度表示，开发了包装在病毒衣壳中的 DNA 模型。该项目的总体目标是了解 DNA 包装到病毒衣壳中的结构、动力学和热力学方面。