PREDICTOR@HOME: PROTEIN STRUCTURE PREDICTION VIA THE WORLD-WIDE-WEB

PREDICTOR@HOME：通过万维网预测蛋白质结构

• 批准号: 7602261
• 负责人: CHARLES L BROOKS
• 金额: $ 4.25万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602261
• 关键词: Bioinformatics; Code; Computer Retrieval of Information on Scientific Projects Database; Computer software; Development; Funding; Grant; Homology Modeling; Institution; Internet; Methods; Modeling; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Source; Structure; Supercomputing; United States National Institutes of Health; base; protein folding; protein structure prediction; simulation; supercomputer; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This core research project is directed toward the development, implementation and application of structural bioinformatics methods to protein structure prediction, loop modeling and homology modeling. Specific efforts have been directed toward the establishment of a WWW-based structure prediction supercomputer utilizing the BOINC (Berkeley Open Infrastructure for Network Computing) middleware (http://boinc.berkeley.edu) and the software packages CHARMM (biomolecular simulation package) and mfold (lattice-based protein folding code, part of the MMTSB Tool Set) or PROSPECTOR_3/TASSER/SPICKER. This supercomputing platform is called Predictor@Home (http://predictor.scripps.edu).

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本核心研究计划旨在发展、实施及应用结构生物资讯学方法于蛋白质结构预测、环结构建模及同源性建模。具体的努力已经指向利用BOINC（Berkeley Open Infrastructure for Network Computing）中间件（http：//www.example.com）和软件包CHARMM（生物分子模拟包）和mfold（基于晶格的蛋白质折叠代码，MMTSB工具集的一部分）或PROSPECTOR_3/TASSER/SPICKER建立基于WWW的结构预测超级计算机。boinc.berkeley.edu这个超级计算平台被称为Predictor@Home（http：predictor.scripps.edu）。