FERROUS AND FERRIC ION CONTAINING MODEL SYSTEMS

含亚铁离子和三价铁离子模型系统

• 批准号: 7602662
• 负责人: KEITH A EARLE
• 金额: $ 0.94万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7602662
• 关键词: Biological; Biological Models; Chemistry; Computer Retrieval of Information on Scientific Projects Database; Free Radicals; Frequencies; Funding; Generations; Grant; Helium; Institution; Ions; Ligands; Liquid substance; Play; Research; Research Personnel; Resolution; Resources; Role; Source; Structure; Study models; System; Technology; Temperature; United States National Institutes of Health; insight

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Ferrous and ferric ions play key roles in many biological systems for the catalytic generation of free radicals through Fenton chemistry. High field ESR, due to its superior orientational resolution and sensitivity to ions that are otherwise ESR silent at lower frequencies, can offer insights into the ligand structure of ferric and ferrous ions and thus inform the elucidation of function of these systems. In order to gain the necessary expertise for studying these heterogeneous systems, we have been studying model compounds, in single crystals, that contain ferrous and ferric ions. The linewidths in ferrous and ferric systems are, generally speaking, quite broad and only readily observable at liquid helium temperatures. Nevertheless, we have obtained well-resolved single crystal spectra on both ferrous and ferric systems and we are developing the technology for studying systems of more direct biological significance.

这个子项目是众多研究子项目之一