BIOINFORMATICS/MICROARRAY SATELLITE CORE-OSU

生物信息学/微阵列卫星核心-OSU

• 批准号: 7610266
• 负责人: ULRICH K MELCHER
• 金额: $ 14.66万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610266
• 关键词: Administrator; Amblyomma; Bioinformatics; Bread; Campylobacter jejuni; Client; Computer Analysis; Computer Retrieval of Information on Scientific Projects Database; Consultations; Core Facility; Cynodon; Data; Educational workshop; Emericella nidulans; Feedback; Funding; Gossypium; Grant; Institution; Journals; Label; Laboratories; Lycopersicon esculentum; Microbe; Nucleic Acids; Oklahoma; Oligonucleotide Microarrays; Organism; Polynucleotides; Preparation; Principal Investigator; Publications; Range; Rattus; Rattus norvegicus; Research; Research Personnel; Resources; Scanning; Scientist; Services; Sorghum; Source; Specialist; Spottings; Students; Synechocystis; System; Ticks; Tomatoes; Training; Training and Education; Triticum aestivum; United States National Institutes of Health; Universities; Wheat; Work; experience; functional genomics; improved; influenzavirus; instrument; peer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Oklahoma State University (OSU) Microarray Core Facility (OMCF) and its associated bioinformatics group, BioinfOSU, provide facilities, consultation, education and training. Their facilities include modern instruments for the preparation of microarrays of oligo- and polynucleotides, for their hybridization to labeled target nucleic acids, for scanning the fluorescent intensities of spots after hybridization and for computational analysis of the results. Staff includes a Ph. D. level microarray specialist with extensive bioinformatics experience, an applications programmer versed in microarray data handling and a systems administrator. To demonstrate that such staff and facilities stimulate and facilitate research in functional genomics, OMCF and BioinfOSU provide workshops and consultation services to investigators of all levels, as well as making their resources generally available. Groups led by more than 25 Principal Investigators use OSU microarray and bioinformatics facilities to study a diverse range of organisms: Amblyomma americanum (lone star tick), Campylobacter jejuni, Cynodon dactylon (bermuda grass), Emericella nidulans, Gossypium hirsutum (cotton), Influenza viruses, Lycopersicon esculentum (tomato), Rattus norvegicus (rat), Sorghum, Synechocystis sp. PCC6803, Triticum aestivum (bread wheat), and various pathogenic microbes. The work supported by the facility has led to publications in peer-reivewed journals (see section G). In addition to training graduate and postdoctoral students, the scientists leading these laboratories annually welcome numerous undergraduate students into their laboratories to participate in the research. Feedback from clients continually improves the facilities? abilities to provide services and advice.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 俄克拉荷马州州立大学（OSU）微阵列核心设施（OMCF）及其相关的生物信息学小组BioinfOSU提供设施、咨询、教育和培训。 他们的设施包括用于制备寡核苷酸和多核苷酸微阵列的现代仪器，用于它们与标记的靶核酸的杂交，用于扫描杂交后斑点的荧光强度以及用于结果的计算分析。 员工包括一名博士。具有丰富生物信息学经验的高级微阵列专家，精通微阵列数据处理的应用程序员和系统管理员。 为了证明这些工作人员和设施促进和促进功能基因组学研究，OMCF和BioinfOSU为各级研究人员提供研讨会和咨询服务，并使其资源普遍可用。 由超过25名主要研究人员领导的小组使用OSU微阵列和生物信息学设施来研究各种各样的生物：美洲花蜱（孤星星蜱）、空肠弯曲杆菌、狗牙根（百慕大草）、构巢裸孢菌（Emericella nidulans）、陆地棉（Gossypium hirsutum）（棉花）、流感病毒、番茄（Lycopersicon esculentum）（番茄）、褐家鼠（Rattus norvegicus）（大鼠）、聚胞藻属（Sorpus）、集胞藻属（Synechocystis sp.）PCC 6803，小麦（面包小麦）和各种病原微生物。 该基金支持的工作已导致在同行评审期刊上发表论文（见G节）。除了培养研究生和博士后学生外，领导这些实验室的科学家每年都欢迎许多本科生进入他们的实验室参与研究。 客户的反馈不断改善设施？提供服务和建议的能力。