Training in Vascular Biology and Medicine

描述（由申请人提供）：该培训补助金的主要重点是从跨学科的角度为来自多个参与部门和部门的研究员提供血管生物学培训，特别强调将基本发现转化为临床研究和实践。血管生物学和医学综合项目的重要性和罕见性得到了科学和临床界以及美国心脏协会和国立卫生研究院等国家组织的认可。在印第安纳州大学，在过去的4年里，我们已经开发了血管生物学和医学的多学科课程，由来自基础和临床部门的32名研究人员组成。其中包括来自10个临床部门和部门的研究人员，以及6个基础科学部门或工程（普渡大学）。该中心为这些研究者之间的合作提供了一个高度互动的环境，这反映在几个新的小组活动的出现和非常积极的参与中，这些活动提供了一个强大的培训环境：血管生物学研讨会系列，血管杂志俱乐部，两个血管研究讨论小组，每个小组的目标都是最终提交PPG或SCOR多研究者资助。洲际弹道导弹中心内部的新合作也直接导致了大量新的联邦资金。在过去的2年中，该中心赞助了血管生物学和医学的校内赠款：在20个提交的提案中，10个基于其科学价值、跨部门性质和扩展到未来资金的前景而被授予;这些直接导致了6个新的联邦或国家赠款-这些相互作用的优点的确证。这种对血管生物学和医学未来的互动愿景正在通过严格的研究培训计划来推进，该计划整合了血管生物学的各个方面，并鼓励将基本发现转移到临床实践中，并培养年轻的研究人员成为该领域的未来领导者。该T32提案旨在为来自临床和基础研究背景的选定博士后研究员提供一个机会，让他们在这个丰富的互动环境中沉浸在选定的实验室中。

DESCRIPTION (provided by applicant): The primary focus of this training grant is to provide vascular biology training to fellows from multiple participating Divisions and Departments, from an interdisciplinary perspective with a particular emphasis on translation of basic findings into clinical research and practice. The importance, as well as rarity, of an integrated program in vascular biology and medicine is recognized by both scientific and clinical communities, and by national organizations such as the American Heart Association, and National Institutes of Health. At Indiana University, over the past 4 years, we have developed a multidisciplinary program in Vascular Biology and Medicine, comprised of 32 investigators from basic as well as clinical departments. These include investigators from 10 clinical divisions and departments, as well as 6 basic science departments or Engineering (Purdue). This center has made possible a highly interactive environment for collaboration among these investigators, which has been reflected in emergence of and very active participation in several new group activities which lend themselves to a robust training environment: a vascular biology seminar series, a vascular journal club, two vascular research discussion groups, each targeted toward the eventual submission of a PPG or SCOR multi-investigator grant. The new collaborations that have occurred within the ICVBM have also led directly to substantial new federal funding. Over the past 2 years, the Center sponsored intramural grants in vascular biology and medicine: of 20 submitted proposals, 10 were awarded based on their scientific merit, interdepartmental nature, and prospects for extension to future funding; and these have led directly to 6 new federal or national grants - a corroboration of the merit of these interactions. This interactive vision for the future of vascular biology and medicine is being advanced by a rigorous research training program integrates all aspects of vascular biology and encourages the transfer of basic discoveries to clinical practice, and which nurtures young investigators to become the future leaders of this field. This T32 proposal is designed to provide an opportunity for selected post-doctoral fellows from both clinical and basic research backgrounds to be immersed in selected laboratories within this rich and interactive environment.