INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTS

描述（由申请人提供）：我们要求继续资助威斯康星大学麦迪逊分校的医学科学培训计划（MSTP）。MSTP在其向医生-科学家提供杰出的综合培训的使命方面取得了重大进展。塑造该计划的核心理念是：（1）医学博士的严谨和口径;和博士学位（2）学生互相学习;及（3）毕业生，虽然学位不同，但会从事翻译研究。三名医生科学家，每个人都积极参与研究，研究生培训和临床活动，指导MSTP。一个学生组织与董事们密切合作。董事还建议由MSTP指导委员会，其中包括从大学的主要学院和学校的教师，并确保MSTP利用培训机会提供给学生在威斯康星大学麦迪逊分校的广度。通常的学生做医学院培训的临床前阶段，同时在四个学期的研讨会/期刊俱乐部课程中熟悉研究方法，并参加研究轮换。研究导师和研究生课程在第二年选择。临床桥接课程促进研究生和医疗工作之间的过渡，并向学生介绍临床研究。医学院的主要临床课程在博士毕业后完成。论文大多数学生论文是在需要在传统的生物和化学科学的强有力的培训领域，但相当数量的学生正在做人口为基础的问题，在工程和再生医学的研究。再生医学项目利用小鼠和人类（WA 01和WA 09）胚胎干细胞。学生产生大量的论文，导致重要的出版物。促进计划凝聚力的活动包括每周一次的研讨会、每年一次的务虚会、每年一次的专题讨论会和定期的社交聚会。为了有一个互动和充满活力的学生群体，我们的目标是为70- 80名学生的整体计划规模为10名学生的班级规模。我们的长期目标是培养一批多样化的医生科学家，他们将对生物医学研究和临床医学实践产生重大影响，因此，将成为学术医学的未来领导者。

DESCRIPTION (provided by applicant): We are requesting continued funding of the Medical Sciences Training Program (MSTP) at the University of Wisconsin-Madison. The MSTP has made significant progress in its mission to provide outstanding, integrated training to physician-scientists. Core philosophies that have shaped the Program are (1) the rigor and caliber of both the M.D. and the Ph.D. training should be equivalent to those of single degree candidates; (2) students learn from one another; and (3) graduates, albeit to variable degrees, will be engaged in translational research. Three physician-scientists, each of whom is active in research, graduate training, and clinical activities, direct the MSTP. A student organization works closely with the directors. Directors also are advised by the MSTP Steering Committee, which includes faculty from the major Colleges and Schools of the University and insures that the MSTP exploits the breadth of training opportunities available to students at UW-Madison. The usual student does the preclinical phase of Medical School training while Becoming acquainted with research methodologies in a four-semester seminar/journal club course and participating in research rotations. Research mentors and graduate programs are chosen in the second year. A clinical bridging curriculum facilitates the transitions between graduate and medical work and also introduces students to clinical research. The major clinical courses of Medical School are done after completion of the Ph.D. thesis. The majority of student theses are in areas that require strong training in the traditional biological and chemical sciences, but a significant number of students are doing research on population-based problems and in engineering and in regenerative medicine. The regenerative medicine projects utilize mouse and human (WA01 and WA09) embryonic stem cells. Students produce substantial theses that result in important publications. Activities that foster program cohesiveness include a weekly seminar, yearly retreat, yearly symposium, and regular social gatherings. To have an interactive and dynamic group of students, we are aiming for a class size of ten students for an overall program size of 70- 80 students. Our long-term goal is to train a diverse group of physician-scientists who will have major impact on biomedical research and the practice of clinical medicine, and hence, will be future leaders in Academic Medicine.