Molecular basis for female age-associated decline in oocyte quality and fertility

许多妇女因为卵子质量不佳而无法生育，这通常是由于年龄的原因。为了开发改进鸡蛋质量的新策略，首先要了解鸡蛋中的关键因素是如何调节的。这个项目将使用最先进的技术来询问我们在鸡蛋中发现的一条关键途径，它可能是导致年龄相关性衰退的原因，并可能掌握使鸡蛋恢复活力的新方法的关键。

Many women cannot have children because of suboptimal egg quality, often due to ageing. In order for novel strategies to be developed for improving egg quality, it will first be important to understand how key factors in eggs are regulated. This project will use state-of-the-art techniques to interrogate a pivotal pathway we have discovered in eggs that could be responsible for age-related decline and could hold the key to new approaches for rejuvenating eggs.