Molecular basis for female age-associated decline in oocyte quality and fertility

女性年龄相关卵母细胞质量和生育能力下降的分子基础

• 批准号: nhmrc : GNT1114631
• 负责人: Dr Dave Listijono
• 金额: $ 4.79万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-basis-female-quality-fertility/1346919
• 关键词: Molecular; basis; female; age; associated

Many women cannot have children because of suboptimal egg quality, often due to ageing. In order for novel strategies to be developed for improving egg quality, it will first be important to understand how key factors in eggs are regulated. This project will use state-of-the-art techniques to interrogate a pivotal pathway we have discovered in eggs that could be responsible for age-related decline and could hold the key to new approaches for rejuvenating eggs.

许多女性由于卵子质量不佳（通常是由于衰老）而无法生育。为了制定提高鸡蛋质量的新策略，首先必须了解鸡蛋中的关键因素是如何调节的。该项目将使用最先进的技术来研究我们在鸡蛋中发现的一个关键途径，该途径可能导致与年龄相关的衰退，并可能掌握使鸡蛋恢复活力的新方法的关键。