Medical Marvels Interactive Translational Research Experience (MITRE)

描述（由申请人提供）：医学的进步在很大程度上取决于公众积极参与生物医学和行为研究。随着将科学发现更快、更有效地转化为医学进步（转化研究）的努力不断增加，公众参与变得更加重要。为了确保积极和知情的公众参与转化生物医学和行为研究，公众教育是必不可少的。该提案的总体目标是通过底特律科学中心（DSC）和密歇根大学（UM）之间的联合伙伴关系，提高公众对转化生物医学和行为研究的认识和理解，并研究科学博物馆的设置和互动研究展览的有效性，以提高公众的研究素养和参与转化研究的意愿。具体来说，UM和DSC提出了两个具体目标：1）开发，建立和评估一个关于转化研究的互动展览，该展览将被整合到即将到来的DSC医学奇迹画廊“医院”中，并将模拟参观者作为“患者”进入医院转化研究中心并同意成为现实生活研究中的“受试者”的体验;和2）开发，实施和评估与密歇根州科学教育课程框架一致的遗传学和遗传学内容的教育研讨会，这将刺激初中和高中学生重视不同社区的转化研究，并考虑从事转化研究。在以社区为基础的参与式研究的精神，从DSC成员和UM技术咨询小组确定的社区咨询委员会将有助于该项目的设计，内容和评估。在拟订、执行和评价过程中，将反复采用利用重点小组、自由文本评论和调查数据的混合方法设计。该项目将产生一个互动的翻译研究展览，预计在未来十年内将有400万至500万不同社会经济背景和年龄范围的人参观。它将促进公众对健康科学转化研究的理解和参与。这种合作可以为DSC开发社区实验室提供一块垫脚石，用于未来的研究工作，以真正基于社区的令人兴奋的格式收集数据并向公众传播有关转化研究的信息。

DESCRIPTION (provided by applicant): Advances in medicine are vitally dependent on active participation of the public in biomedical and behavioral research. As efforts increase to translate scientific discovery more quickly and effectively into advances in medicine (translational research), public participation becomes even more critical. To assure active and informed public participation in translational biomedical and behavioral research, public education is essential. The overarching goals of this proposal are to increase public knowledge and understanding of translational biomedical and behavioral research through a joint partnership between the Detroit Science Center (DSC) and the University of Michigan (UM), and to examine the setting of a science museum and effectiveness of an interactive research exhibit for increasing public research literacy and willingness to participate in translational research. Specifically, UM and the DSC propose two specific aims: 1) to develop, build and evaluate an interactive exhibit about translational research that will be integrated into the forthcoming DSC Medical Marvels Gallery "hospital", and will simulate the visitor's experience as a "patient" entering into a hospital translational research center and providing consent to be a "subject" in a real-life research study; and 2) to develop, implement and evaluate an educational workshop with genetics and heredity content consistent with the Michigan Curriculum Framework for science education that will stimulate middle and high school students to value translational research for diverse communities and consider a career in translational research. In the spirit of community-based participatory research, a Community Advisory Board identified from the DSC membership and a UM Technical Advisory Panel will contribute to the design, content, and evaluation of the project. A mixed methods design utilizing focus groups, free-text comments and survey data will be used iteratively in the formulation, implementation and evaluation. This project will produce an interactive translational research exhibit that will be visited by an estimated four to five million people of diverse socioeconomic backgrounds and age ranges over the next ten years. It will promote public understanding of and participation in health sciences translational research. This collaboration could provide a stepping-stone for developing a community laboratory at the DSC for future research efforts to collect data from and disseminate information to the public about translational research in an exciting format that is truly community-based.