Molecular dissection of proteins that regulate the invasion of Toxoplasma gondii into human cells

调节弓形虫侵入人体细胞的蛋白质的分子解剖

• 批准号: nhmrc : 575523
• 负责人: A/Pr Christopher Tonkin
• 金额: $ 25.84万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-dissection-proteins-human-cells/116229
• 关键词: Molecular; dissection; proteins; regulate; invasion

Toxoplasma gondii is an obligate intracellular parasite responsible for congenital birth defects and disease of immuno-compromised individuals. I propose to identify and characterize molecules essential for T. gondii invasion into human cells. These represent novel targets for therapeutic intervention for disease caused by this important organism.

刚地弓形虫是一种专性细胞内寄生虫负责先天性出生缺陷和免疫受损个体的疾病。我建议鉴定和表征弓形虫入侵人体细胞所必需的分子。这代表了这种重要生物体引起的疾病的治疗干预的新靶点。