Regulation of toxoplasma by the NLRP1 inflammasome
Regulation of toxoplasma by the NLRP1 inflammasome
批准号:
nhmrc : 1057815
负责人:
A/Pr Christopher Tonkin
金额:
$41.55万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
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英文摘要
Toxoplasmosa is an endemic pathogen worldwide, approaching 80% of the population in some areas, with a large burden of disease, particularly of immunocompromised and pregnant individuals. Our preliminary data identifies a receptor protein in immune cells that detects Toxoplasma. This can defeat the parasite, but also causes pathology for the host. The outcome of our project will work out what part of Toxoplasma is recognized by this receptor, with significance for the treatment of Toxoplasmosis.
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会议论文
Targeting acute and chronic toxoplasmosis
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批准号:nhmrc : GNT1123218
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项目类别:Project Grants
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资助金额:$53.11万
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财政年份:2017
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负责人:A/Pr Christopher Tonkin
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依托单位:
Targeting acute and chronic toxoplasmosis
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批准号:nhmrc : 1123218
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项目类别:Project Grants
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资助金额:$36.24万
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财政年份:2017
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负责人:A/Pr Christopher Tonkin
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依托单位:
Functional analysis of the Toxoplasma Myosin driving tissue dissemination and host cell invasion
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批准号:nhmrc : 1047806
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项目类别:Project Grants
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资助金额:$50.89万
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财政年份:2013
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负责人:A/Pr Christopher Tonkin
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依托单位:
Functional Dissection of Invasion Motor Regulation in Toxoplasma gondii
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批准号:nhmrc : 1025598
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项目类别:Project Grants
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资助金额:$33.37万
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财政年份:2012
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负责人:A/Pr Christopher Tonkin
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依托单位:
Sequence requirements for targeting parasite proteins to the red blood cell membrane in the malaria parasite P. falcipar
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批准号:nhmrc : 575513
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项目类别:Early Career Fellowships
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资助金额:$0.48万
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财政年份:2009
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负责人:A/Pr Christopher Tonkin
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依托单位:
Molecular dissection of proteins that regulate the invasion of Toxoplasma gondii into human cells
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批准号:nhmrc : 575523
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项目类别:Career Development Fellowships
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资助金额:$25.84万
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财政年份:2009
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负责人:A/Pr Christopher Tonkin
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依托单位:
Regulation of actin polymerization during malaria parasite invasion of the human erythrocyte
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批准号:nhmrc : 516747
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项目类别:NHMRC Project Grants
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资助金额:$21.21万
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财政年份:2008
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负责人:A/Pr Christopher Tonkin
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依托单位:
Sequence requirements for targeting parasite proteins to the red blood cell membrane in the malaria parasite P. falcipar
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批准号:nhmrc : 356264
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项目类别:Early Career Fellowships
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资助金额:$18.1万
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财政年份:2005
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负责人:A/Pr Christopher Tonkin
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依托单位:
国内基金
海外基金
弓形虫MAG嵌合型类病毒颗粒转基因植物快速高效表达技术平台的建立及其动物口服免疫机制的探索
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批准号:30872204
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项目类别:面上项目
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资助金额:33.0万元
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批准年份:2008
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负责人:周晓红
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依托单位:
弓型虫cDNA库构建的研究
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批准号:39170692
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项目类别:面上项目
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资助金额:3.0万元
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批准年份:1991
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负责人:夏爱娣
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依托单位: