Targeting acute and chronic toxoplasmosis

针对急性和慢性弓形虫病

• 批准号: nhmrc : GNT1123218
• 负责人: A/Pr Christopher Tonkin
• 金额: $ 53.11万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-acute-chronic-toxoplasmosis/1347327
• 关键词: Targeting; acute; chronic; toxoplasmosis

One third of the world's population is infected with the protozoan parasite, Toxoplasma gondii, which can cause life-threatening infections. This proposal will utilize new analytical technologies to understand how these parasites are able to survive in a wide variety of different host cells, how they manage to persist within brain and muscle tissue for the life of the patient and how infection may be linked to mental health disorders, such as schizopohrenia.

世界上三分之一的人口感染了原生动物寄生虫——刚地弓形虫，这种寄生虫可导致危及生命的感染。该提案将利用新的分析技术来了解这些寄生虫如何能够在各种不同的宿主细胞中生存，它们如何设法在患者的大脑和肌肉组织中持续存在，以及感染如何与精神分裂症等精神健康障碍联系起来。