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CLINICAL TRIAL: A PHASE 2 STUDY OF AZD6244 IN ADVANCED OR METASTATIC HEPATOCELLU

CLINICAL TRIAL: A PHASE 2 STUDY OF AZD6244 IN ADVANCED OR METASTATIC HEPATOCELLU
临床试验:AZD6244 在晚期或转移性肝细胞中的 2 期研究
批准号:
7950892
负责人:
John David Roberts
金额:
$1.4万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-12-01 至 2009-11-30

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Studies of primary tumor samples and cell lines have shown constituitive activation or over-activation of the MAP kinase pathways in cancers of the pancreas, colon, lung, ovary and kidney. Therefore agents targeting the RAS/RAF/MEK/EFK pathway might inhibit oncogenic signalling in tumor cells.
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CLINICAL TRIAL: COMBINED TREATMENT WITH BORTEZOMIB & DACARBAZINE
  • 批准号:
    8166535
  • 项目类别:
  • 资助金额:
    $2.24万
  • 财政年份:
    2009
  • 负责人:
    John David Roberts
  • 依托单位:
CLINICAL TRIAL: PILOT/PHASE 1 STUDY OF ZOLEDRONIC ACID (ZOMETA ) IN SICKLE CELL
  • 批准号:
    7950882
  • 项目类别:
  • 资助金额:
    $0.09万
  • 财政年份:
    2008
  • 负责人:
    John David Roberts
  • 依托单位:
CLINICAL TRIAL: COMBINED TREATMENT WITH BORTEZOMIB & DACARBAZINE
  • 批准号:
    7950860
  • 项目类别:
  • 资助金额:
    $3.22万
  • 财政年份:
    2008
  • 负责人:
    John David Roberts
  • 依托单位:
Clinical Protocol and Data Management
  • 批准号:
    7698841
  • 项目类别:
  • 资助金额:
    $2.1万
  • 财政年份:
    2008
  • 负责人:
    John David Roberts
  • 依托单位:
海外基金