Renovations at Johns Hopkins University to Support Expanded Macaque Production

约翰·霍普金斯大学进行翻修以支持扩大猕猴生产

• 批准号: 7627411
• 负责人: ROBERT J. ADAMS
• 金额: $ 50万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-16 至 2012-01-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7627411
• 关键词: Animal Model; Breeding; Deterioration; Development; Emergency Situation; Engineering; Ensure; Farming environment; Funding; Grant; Growth; Laboratory Animals; Macaca; Macaca mulatta; Macaca nemestrina; Production; Request for Proposals; Research; Resources; Universities; Water; animal care; meetings; nonhuman primate; programs

DESCRIPTION (provided by applicant): This proposal requests $500,000 to partially fund the renovation and refurbishment of Building 12 at the Johns Hopkins Research Farm to accommodate the growth of a P40 grant supported SPF Pigtail macaque colony (Robert J. Adams, PI, P40 RR019995-01A2, Development of an SPF Macaca nemestrina Breeding Colony). The animal care and use program of Johns Hopkins University is large and highly diversified involving a broad spectrum of laboratory animal species. Non-human primate use has long been a prominent feature of the program, and a rhesus monkey breeding colony (Macaca mulatta) has been maintained on the Hopkins Research Farm campus for decades to ensure that an ample supply of SPF rhesus macaques was available for our research programs. Beginning in 2003, we embarked upon the development of an SPF breeding colony for pigtail macaques (Macaca nemestrina) using institutional resources to meet the growing needs for this animal model in JHU research programs and to alleviate the difficulties we had encountered in obtaining this species for outside colonies. Building 12 has not been used for over 10 years, and has undergone some deterioration, but after extensive review by outside Architects and Engineers, it has been determined that the building can be renovated and refurbished relatively easily. Building 12 is adjacent to Building 13 in which the colony now resides. The two buildings will share an emergency electrical generator and water well requested as part of this proposal.

描述（由申请人提供）：本提案要求50万美元用于部分资助约翰霍普金斯研究农场12号楼的翻新和整修，以适应P40赠款支持的SPF猪尾猕猴群的增长（Robert J.亚当斯，PI，P40 RR 019995 - 01 A2，SPF猕猴繁殖群的发展）。约翰霍普金斯大学的动物护理和使用计划是大型的，高度多样化的，涉及广泛的实验室动物物种。长期以来，非人灵长类动物的使用一直是该计划的一个突出特点，几十年来，霍普金斯研究农场校园一直保持着一个恒河猴繁殖群（Macaca mulatta），以确保我们的研究计划有充足的SPF恒河猴供应。从2003年开始，我们开始使用机构资源开发猪尾猕猴（Macaca nemestrina）的SPF繁殖群，以满足JHU研究计划中对这种动物模型日益增长的需求，并减轻我们在获得该物种时遇到的困难。12号楼已有10多年没有使用，并已出现一些损坏，但经外部建筑师和工程师广泛审查后，确定该楼可以相对容易地进行翻修和翻新。12号楼与13号楼相邻，殖民地现在就住在13号楼里。这两座大楼将共用一个应急发电机和水井，这是本提案的一部分。