Appalachian Tri-State NODE

阿巴拉契亚三州节点

• 批准号: 7493035
• 负责人: DENNIS C DALEY
• 金额: $ 125万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7493035
• 关键词: Appalachian; Tri; State; NODE

DESCRIPTION (provided by applicant): This application is in response to RFA DA-05-001 to join the National Institute of Drug Abuse's (NIDA) Clinical Trials Network (CTN) as the "Appalachian Tri-State" (ATS) Node to work with other CTN Nodes to conduct multi-site clinical trials in the community. ATS will serve an important geographic area with many rural and underserved populations. This Node includes a research group at Western Psychiatric Institute and Clinic (WPIC) of the University of Pittsburgh Medical Center in partnership with five community treatment providers (CTPs) in West Virginia, Eastern Ohio and Western Pennsylvania. The heterogeneity of the clinical populations served in these CTPs will allow the CTPs to conduct efficacy and effectiveness trials with a range of providers and clinical populations. Components of the ATS Node include: (1) an experienced group of CTPs in rural and urban locations serving diverse groups of patients in many types of drug abuse clinical programs with access to over 13,000 patients annually; (2) an established research infrastructure within the Regional Research Treatment Center (RRTC) at WPIC for conducting behavioral, pharmacotherapy and combined clinical trials and related activities; (3) a strong training and education component that can provide research and clinical training and disseminate research findings; (4) an administrative structure to coordinate activities among the ATS Node components and to promote optimal communication and cooperation within the Node and with NIDA and the National CTN; and (5) a portfolio of technology transfer, training and dissemination activities. The RRTC and CTPs have collaborated during the past four years to build an infrastructure, establish bi-directional communication, and conduct two pilot studies. Our aims are to: (1) develop and maintain a regional network of CTPs to participate in clinical trials, (2) develop, direct, and participate in clinical trials for the National CTN, (3) provide information to, and training opportunities for regional treatment providers, (4) develop, promote, and implement treatment distribution efforts, and (5) contribute to the development of methods for dissemination of research-based treatment findings, and the integration of empirically-validated assessment and treatment methods into the ongoing activities of community healthcare delivery facilities.

描述（由申请人提供）： 本申请是对RFA DA-05-001的回应，以加入美国国家药物滥用研究所（NIDA）临床试验网络（CTN），作为“阿巴拉契亚三州”（ATS）节点，与其他CTN节点合作，在社区开展多中心临床试验。安非他明类兴奋剂将服务于一个重要的地理区域，那里有许多农村人口和得不到充分服务的人口。该节点包括匹兹堡大学医学中心西部精神病研究所和诊所（WPIC）的一个研究小组，与西弗吉尼亚州、东俄亥俄州和西宾夕法尼亚州的五个社区治疗提供者（CTP）合作。这些CTP中服务的临床人群的异质性将允许CTP与一系列提供者和临床人群进行疗效和有效性试验。安非他明类兴奋剂联络点的组成部分包括：（1）一组经验丰富的农村和城市现金转拨方案，在许多类型的药物滥用临床方案中为各种患者群体提供服务，每年可接触13，000多名患者;（2）在西太平洋研究中心区域研究治疗中心内建立了研究基础设施，用于开展行为、药物治疗和综合临床试验及相关活动;（3）一个强有力的培训和教育组成部分，能够提供研究和临床培训并传播研究成果;（4）一个行政结构，协调安非他明类兴奋剂节点各组成部分之间的活动，并促进节点内部以及与国家药物开发局和国家技术中心网络的最佳沟通与合作;（5）一系列技术转让、培训和传播活动。在过去的四年里，区域研究和培训中心和现金转拨方案合作建立了基础设施，建立了双向通信，并进行了两项试点研究。我们的目标是：（1）开发和维护参与临床试验的CTP区域网络，（2）开发、指导和参与国家CTN的临床试验，（3）为区域治疗提供者提供信息和培训机会，（4）开发、促进和实施治疗分配工作，和（5）促进传播基于研究的治疗结果的方法的发展，并将经医学验证的评估和治疗方法整合到社区医疗保健提供机构的持续活动中。