Planning and Evaluation Core

规划和评估核心 本节介绍规划和评估核心。规划与评价的总体目标 核心是评估合作的进展情况。为此，规划和评价核心将 审查合作伙伴关系的各个组成部分，以确保协作的目标和目的 都相遇了。在本核心中设立的委员会将定期举行会议，审查和确定短期和长期 目标、项目进展，并将审查开发核心的新试点项目。 内部流程 内部咨询委员会(IAC)由FHCRC和NMSU的科学家组成。每一个人 是根据他/她在与该应用相关的领域的知识和专业知识而被选中的。IAC 以下将简要介绍其成员资格。 新墨西哥州会员 卡尔·肯德尔。肯德尔博士是斯坦·富尔顿健康差异捐赠主席的新任主席兼主任 为西南健康差距研究中心工作。他还担任以下机构的副院长 国立密歇根州立大学健康与人类服务学院。肯德尔在杜兰大学的职业生涯结束后，来到了NMSU 路易斯安那州大学公共卫生和热带医学院和约翰霍普金斯大学彭博社 公共卫生学院。肯德尔博士接受了杜兰大学授予的2002年度杰出研究教师奖， 2003年、2004年和2005年。他与杜兰癌症中心和路易斯安那州的同事合作 在癌症联合会，他指导初级教员制定加强乳腺癌筛查的建议 在非洲裔美国人中。他与40多个国家的同事合作， 解决母婴疾病、病媒传播疾病和艾滋病毒/艾滋病等全球性问题。目前 肯德尔在8个国家管理项目，在其中4个国家有全职员工。肯德尔博士说得很流利 曾在西班牙和危地马拉教授大学研究生课程。 维马尔·柴坦瓦。在成为NMSU负责研究、研究生研究和国际事务的副校长之前 项目2006年7月，柴坦尼亚博士担任先进材料处理与分析中心主任 中佛罗里达大学(UCF)AMPAC中心。他也是UCF材料公司的主管 科学与工程计划及其材料表征设施。Chaitanya博士收到了 2002年获得中佛罗里达大学研究成就奖，1999年荣获UCF领导力奖。 他五次获得他所在的学术部门的年度研究人员奖。他有一个博士学位。 来自巴尔的摩约翰霍普金斯大学的材料科学和工程硕士学位 南卡罗来纳州克莱姆森大学生物工程和机械工程学士学位 来自印度巴罗达M.S.大学。 弗雷德·哈钦森癌症研究中心成员 哈米特·S·马利克。马利克博士是FHCRC的助理成员，也是 华盛顿大学基因组科学。马利克博士的实验室对生物进化研究感兴趣 基因冲突，以深入了解其机制和后果。基因组是微不足道的 由不同遗传实体组成的集团，每个实体都试图最大化自己的进化成功，通常是在 它们的基因组邻居付出了巨大的代价。这可能会给寄主有机体带来问题。深入了解 马利克博士的实验室研究了着丝粒、可移动的遗传元素和快速进化的蛋白质的这些机制 在果蝇身上。马利克博士将在生物学和果蝇研究方面提供丰富的专业知识。 朱利安·西蒙。西蒙博士是FHCRC的准成员，也是 华盛顿大学分子和细胞生物学专业。他的实验室的目的是发现新的 抗癌药物。这是通过使用癌细胞的遗传背景作为药物靶点来实现的。这个 第二个广泛的策略是利用化学遗传学来寻找更好的抗癌药物。实验室中的其他项目 包括以核苷酸还原酶为策略研究错配修复突变体的遗传相互作用 用于鉴定治疗具有错配修复缺陷的肿瘤的药物。西蒙博士参与了 在U56中工作，并对协作如何运作有很好的理解。 临时成员‘’ 每当在U54协作中呼吁提出新的建议时，都会召开一个“研究小组”，以 审查和批评这些提案。我们在U56颁奖期间遵循了这种格式，并发现这是一种 将提案与提案所涵盖领域的专业知识相匹配的有效方法。来自两个国家的成员 咨询委员会将确定和招募机构，以审查提案(见下文)。这些评审员将 成立一个研究小组，对收到的建议书进行讨论和排名，并提出建议 改进。

PLANNING AND EVALUATION CORE This section describes the Planning and Evaluation Core. The overall goal of the Planning and Evaluation Core is to assess the progress of the collaboration. Toward that end, the Planning and Evaluation Core will review the various components of the partnership to ensure that the goals and objectives of the collaboration are met. The committees established in this Core will meet regularly to review and establish short- and longterm goals, progress of the projects, and will review new pilot projects for the development Core. Internal Processes The Internal Advisory Committee (IAC) is comprised of scientists at the FHCRC and NMSU. Each individual was selected based on his/her knowledge and expertise of areas related to this application. The IAC membership is briefly described below. New Mexico Members Carl Kendall. Dr. Kendall is the new holder of the Stan Fulton Endowed Chair in Health Disparities and director for the Southwest Center for Health Disparities Research. He also serves as Associate Dean for Research for the College of Health and Human Services at NMSU. Kendall is new to NMSU after a career at the Tulane University School of Public Health and Tropical Medicine in Louisiana, and The Johns Hopkins Bloomberg School of Pubic Health. Dr. Kendall received the distinguished research faculty award from Tulane for 2002, 2003, 2004 and 2005. He has collaborated with colleagues at the Tulane Cancer Center and the Louisiana Cancer Consortium where he mentored junior faculty to develop proposals to enhance breast cancer screening among African-American populations. He has collaborated with colleagues in more than 40 countries to address global problems of maternal and childhood illnesses, vector-borne diseases, and HIV/AIDS. Currently Kendall manages projects in eight countries with full-time staff in four of those countries. Dr. Kendall is fluent in Spanish and has taught university graduate courses in Spain and Guatemala. Vimal Chaitanva. Before becoming the NMSU Vice President for Research Graduate Studies and International Programs in July 2006, Dr. Chaitanya was the director of the Advanced Materials Processing and Analysis Center (AMPAC) at the University of Central Florida (UCF). He was also the director of UCF's Materials Science and Engineering program and its Materials Characterization Facility. Dr. Chaitanya received the University of Central Florida's Research Achievement Award in 2002 and the UCF Leadership Award in 1999. He is a five-time winner of his academic department's Researcher of the Year award. He has a Ph.D. in materials science and engineering from The Johns Hopkins University in Baltimore, a master's degree in bioengineering from Clemson University in South Carolina, and a bachelor's degree in mechanical engineering from M.S. University of Baroda, India. Fred Hutchinson Cancer Research Center Members Harmit S. Malik. Dr. Malik is an Assistant Member at the FHCRC and an Affiliate Assistant Professor of Genome Sciences at the University of Washington. Dr. Malik's lab is interested in evolutionary studies of genetic conflict to gain insights into their mechanisms and consequences. Genomes are a tenuous conglomerate of different genetics entities, each trying to maximize their own evolutionary success, often at great cost to their genomic neighbors. This can create problems for the host organism. To gain insights into these mechanisms, Dr. Malik's lab studies centromeres, mobile genetic elements, and rapidly evolving proteins in Drosophila. Dr. Malik will provide great expertise in biology and the drosophila studies. Julian Simon. Dr. Simon is an Associate Member at the FHCRC and an Affiliate Associate Professor in the Molecular and Cellular Biology Program at the University of Washington. The aim of his lab is to identify new anticancer drugs. This is done through using the genetic context of the cancer cell as the drug target. The second broad strategy is to use chemical genetics to find better anticancer drugs. Other projects in the lab include the study of genetic interactions of mismatch repair mutants with ribonucleotide reductase as a strategy for the identification of drugs for the treatment of tumors with mismatch repair defects. Dr. Simon was involved in the U56 and has excellent understanding of how the collaboration operates. Ad Hoc Members ' ' Whenever there is a call for new proposals within the U54 collaboration, a "study section" will be convened to review and critique the proposals. We followed this format during the U56 award and found this to be an effective way to match proposals with expertise in the areas covered by the proposal. Members from both institutions will be identified and recruited by the IAC to review proposals (see below). These reviewers will form a study section to discuss and rank the proposals received and to make recommendations for improvements.