Planning and Evaluation Core

规划与评估核心

• 批准号: 7686795
• 负责人: BETI THOMPSON
• 金额: $ 7.49万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7686795
• 关键词: AIDS/HIV problem; Achievement; Address; Advisory Committees; Affect; African American; Antineoplastic Agents; Applications Grants; Area; Award; Bachelor' s Degree; Baltimore; Basic Science; Biology; Biology, Other; Biomedical Engineering; Breast Cancer Detection; Cancer Center; Centromere; Charge; Chemistry; Childhood; Clinical Sciences; Closure; Collaborations; Committee Members; Committee Membership; Communication; Computational Biology; Conflict (Psychology); Country; Critiques; Decision Making; Defect; Development; Development Plans; Doctor of Philosophy; Drosophila genus; Drosophila inturned protein; Drug Delivery Systems; Educational process of instructing; Educational workshop; Engineering; Ensure; Environment; Epidemiologic Methods; Epidemiology; Evaluation; Event; Faculty; Failure; Florida; Fred Hutchinson Cancer Research Center; Funding; Funding Mechanisms; Future; Genetic; Genome; Genomics; Goals; Grant; Guatemala; Health; Health Sciences; Hearing; Human; Human Biology; India; Individual; Institutes; Institution; International; Internet; Interview; Knowledge; Laboratories; Lead; Leadership; Left; Letters; Logistics; Louisiana; Mails; Malignant Neoplasms; Master' s Degree; Mechanics; Mentors; Methods; Mismatch Repair; Mobile Genetic Elements; Molecular and Cellular Biology; New Mexico; Newsletter; Numbers; Operative Surgical Procedures; Organism; Peer Review; Persons; Pharmaceutical Preparations; Pilot Projects; Population; Preparation; Procedures; Process; Production; Proteomics; Protocols documentation; Public Health; Public Health Schools; Publications; Published Comment; Purpose; Recommendation; Recruitment Activity; Reporting; Request for Proposals; Research; Research Infrastructure; Research Personnel; Resources; Ribonucleotide Reductase; Role; Running; Schedule; Schools; Science; Scientist; Score; Services; Site; Site Visit; South Carolina; Spain; Specific qualifier value; Structure; Students; Study Section; Survey Methodology; Time; Tropical Medicine; United States National Institutes of Health; Universities; Update; Vector-transmitted infectious disease; Visit; Washington; Work; Writing; base; cancer cell; career; chemical genetics; college; cost; day; desire; expectation; experience; health disparity; improved; innovation; insight; interest; member; mutant; novel strategies; outreach; outreach program; professor; programs; sound; spelling; success; symposium; tumor

PLANNING AND EVALUATION CORE This section describes the Planning and Evaluation Core. The overall goal of the Planning and Evaluation Core is to assess the progress of the collaboration. Toward that end, the Planning and Evaluation Core will review the various components of the partnership to ensure that the goals and objectives of the collaboration are met. The committees established in this Core will meet regularly to review and establish short- and longterm goals, progress of the projects, and will review new pilot projects for the development Core. Internal Processes The Internal Advisory Committee (IAC) is comprised of scientists at the FHCRC and NMSU. Each individual was selected based on his/her knowledge and expertise of areas related to this application. The IAC membership is briefly described below. New Mexico Members Carl Kendall. Dr. Kendall is the new holder of the Stan Fulton Endowed Chair in Health Disparities and director for the Southwest Center for Health Disparities Research. He also serves as Associate Dean for Research for the College of Health and Human Services at NMSU. Kendall is new to NMSU after a career at the Tulane University School of Public Health and Tropical Medicine in Louisiana, and The Johns Hopkins Bloomberg School of Pubic Health. Dr. Kendall received the distinguished research faculty award from Tulane for 2002, 2003, 2004 and 2005. He has collaborated with colleagues at the Tulane Cancer Center and the Louisiana Cancer Consortium where he mentored junior faculty to develop proposals to enhance breast cancer screening among African-American populations. He has collaborated with colleagues in more than 40 countries to address global problems of maternal and childhood illnesses, vector-borne diseases, and HIV/AIDS. Currently Kendall manages projects in eight countries with full-time staff in four of those countries. Dr. Kendall is fluent in Spanish and has taught university graduate courses in Spain and Guatemala. Vimal Chaitanva. Before becoming the NMSU Vice President for Research Graduate Studies and International Programs in July 2006, Dr. Chaitanya was the director of the Advanced Materials Processing and Analysis Center (AMPAC) at the University of Central Florida (UCF). He was also the director of UCF's Materials Science and Engineering program and its Materials Characterization Facility. Dr. Chaitanya received the University of Central Florida's Research Achievement Award in 2002 and the UCF Leadership Award in 1999. He is a five-time winner of his academic department's Researcher of the Year award. He has a Ph.D. in materials science and engineering from The Johns Hopkins University in Baltimore, a master's degree in bioengineering from Clemson University in South Carolina, and a bachelor's degree in mechanical engineering from M.S. University of Baroda, India. Fred Hutchinson Cancer Research Center Members Harmit S. Malik. Dr. Malik is an Assistant Member at the FHCRC and an Affiliate Assistant Professor of Genome Sciences at the University of Washington. Dr. Malik's lab is interested in evolutionary studies of genetic conflict to gain insights into their mechanisms and consequences. Genomes are a tenuous conglomerate of different genetics entities, each trying to maximize their own evolutionary success, often at great cost to their genomic neighbors. This can create problems for the host organism. To gain insights into these mechanisms, Dr. Malik's lab studies centromeres, mobile genetic elements, and rapidly evolving proteins in Drosophila. Dr. Malik will provide great expertise in biology and the drosophila studies. Julian Simon. Dr. Simon is an Associate Member at the FHCRC and an Affiliate Associate Professor in the Molecular and Cellular Biology Program at the University of Washington. The aim of his lab is to identify new anticancer drugs. This is done through using the genetic context of the cancer cell as the drug target. The second broad strategy is to use chemical genetics to find better anticancer drugs. Other projects in the lab include the study of genetic interactions of mismatch repair mutants with ribonucleotide reductase as a strategy for the identification of drugs for the treatment of tumors with mismatch repair defects. Dr. Simon was involved in the U56 and has excellent understanding of how the collaboration operates. Ad Hoc Members ' ' Whenever there is a call for new proposals within the U54 collaboration, a "study section" will be convened to review and critique the proposals. We followed this format during the U56 award and found this to be an effective way to match proposals with expertise in the areas covered by the proposal. Members from both institutions will be identified and recruited by the IAC to review proposals (see below). These reviewers will form a study section to discuss and rank the proposals received and to make recommendations for improvements.

规划和评价核心 本节介绍规划和评价核心。规划和评价的总体目标 核心是评估合作的进展。为此，规划和评价核心将 审查伙伴关系的各个组成部分，以确保合作的目标和宗旨 得到满足。本核心中设立的委员会将定期开会，审查并建立短期和长期 目标，项目的进展情况，并将审查新的试点项目的发展核心。 内部流程 内部咨询委员会（IAC）由FHCRC和NMSU的科学家组成。每个单独 根据他/她在与此应用程序相关的领域的知识和专业知识进行选择。伊航 成员情况简述如下。 新墨西哥州成员 卡尔·肯德尔。肯德尔博士是新的保持器的斯坦富尔顿捐赠主席在健康差距和主任 西南健康差异研究中心他还担任研究副院长， NMSU健康与公众服务学院。肯德尔是新的NMSU后，在杜兰职业生涯 路易斯安那州的公共卫生和热带医学大学学院和约翰霍普金斯彭博社 公共卫生学院。肯德尔博士获得了2002年杜兰大学颁发的杰出研究教师奖， 2003年、2004年和2005年。他与杜兰癌症中心和路易斯安那州的同事合作， 癌症联盟，他指导初级教师制定加强乳腺癌筛查的建议 在非裔美国人中。他与40多个国家的同事合作， 解决孕产妇和儿童疾病、病媒传播疾病和艾滋病毒/艾滋病等全球性问题。目前 Kendall管理着八个国家的项目，在其中四个国家有全职工作人员。肯德尔医生很流利 曾在西班牙和危地马拉教授大学研究生课程。 Vandi Chaitanva.在成为NMSU副总裁研究生学习和国际 2006年7月，Chaitanya博士担任高级材料处理和分析中心主任， 中心（AMPAC）在中央佛罗里达大学（UCF）。他也是UCF的材料总监 科学与工程计划及其材料表征设施。Chaitanya博士收到了 2002年获得中央佛罗里达大学的研究成就奖，1999年获得UCF领导奖。 他是他的学术部门的年度研究员奖的五次获奖者。他有博士学位。在 美国巴尔的摩约翰霍普金斯大学材料科学与工程系， 他在南卡罗来纳州的克莱姆森大学获得生物工程学学士学位，并获得机械工程学士学位 从MS印度巴罗达大学。 弗雷德哈钦森癌症研究中心成员 哈米特·S马利克马利克博士是在FHCRC助理成员和附属助理教授 华盛顿大学的基因组科学。马利克博士的实验室对进化研究很感兴趣 遗传冲突，以深入了解其机制和后果。基因组是一个脆弱的 不同遗传实体的联合体，每个实体都试图最大化自己的进化成功，通常在 对它们的基因组邻居来说是巨大的代价。这可能会给宿主生物带来问题。来深入了解 为了研究这些机制，马利克博士的实验室研究了着丝粒、移动的遗传元件和快速进化的蛋白质 在果蝇中。马利克博士将提供生物学和果蝇研究方面的专业知识。 朱利安·西蒙西蒙博士是在FHCRC的准会员和附属副教授在 华盛顿大学分子和细胞生物学项目。他的实验室的目的是识别新的 抗癌药这是通过使用癌细胞的遗传背景作为药物靶标来完成的。的 第二大战略是利用化学遗传学来寻找更好的抗癌药物。实验室中的其他项目 包括研究错配修复突变体与核糖核苷酸还原酶的遗传相互作用， 用于鉴定治疗具有错配修复缺陷的肿瘤的药物。西蒙医生参与了 在U56，并有很好的理解如何合作运作。 临时成员"" 每当U54合作中需要新的提案时，将召集一个"研究组"， 审查和评论提案。我们在U56颁奖期间遵循了这种格式，并发现这是一个 将建议书与建议书所涉领域的专门知识相匹配的有效方法。双方成员 独立咨询委员会将确定和招聘机构来审查提案（见下文）。这些审查员将 成立一个研究组，讨论收到的建议，并对它们进行排序， 改进.