GENETICS OF RECEPTORS - MEDICATED ENDOCYTOSIS

受体遗传学 - 药物内吞作用

• 批准号: 7731330
• 负责人: MONTY KRIEGER
• 金额: $ 0.19万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731330
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Endocytosis; Funding; Genetic; Grant; HDL receptor; High Density Lipoproteins; Human; Institution; Lipoprotein Receptor; Lipoproteins; Low-Density Lipoproteins; Mediating; Plasma; Research; Research Personnel; Resources; Serum; Source; United States National Institutes of Health; lipid transport; receptor; receptor binding

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Study will isolate Lipoproteins from human plasma to study lipoprotein receptors, especially LDL and HDL. The precise mechanisms by which these receptors bind their liproproteins and mediate lipid transport are unknowns for the HDL receptor, and we will use liproprotein-deficient serum to study the mechanisms.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 研究将使脂蛋白从人血浆分离到研究脂蛋白受体，尤其是LDL和HDL。这些受体结合其脂蛋白和介导脂质转运的确切机制是HDL受体的未知数，我们将使用缺乏蛋白质缺陷型血清来研究该机制。