GENETICS OF RECEPTORS - MEDICATED ENDOCYTOSIS

受体遗传学 - 药物内吞作用

• 批准号: 7731330
• 负责人: MONTY KRIEGER
• 金额: $ 0.19万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731330
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Endocytosis; Funding; Genetic; Grant; HDL receptor; High Density Lipoproteins; Human; Institution; Lipoprotein Receptor; Lipoproteins; Low-Density Lipoproteins; Mediating; Plasma; Research; Research Personnel; Resources; Serum; Source; United States National Institutes of Health; lipid transport; receptor; receptor binding

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Study will isolate Lipoproteins from human plasma to study lipoprotein receptors, especially LDL and HDL. The precise mechanisms by which these receptors bind their liproproteins and mediate lipid transport are unknowns for the HDL receptor, and we will use liproprotein-deficient serum to study the mechanisms.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 研究将从人血浆中分离脂蛋白，以研究脂蛋白受体，特别是LDL和HDL。这些受体结合其脂蛋白并介导脂质转运的确切机制对于HDL受体尚不清楚，我们将使用脂蛋白缺乏的血清来研究这些机制。