APOPTOTIC BIOMARKERS OF PERIODONTAL DISEASE

牙周疾病的细胞凋亡生物标志物

• 批准号: 7603835
• 负责人: Yvonne L Kapila
• 金额: $ 0.07万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603835
• 关键词: Apoptotic; Bacteria; Biological Markers; Cells; Computer Retrieval of Information on Scientific Projects Database; Dental; Diagnostic tests; Disease Progression; Funding; Grant; Institution; Liquid substance; Oral cavity; Patients; Periodontal Diseases; Proteins; Purpose; Research; Research Personnel; Resources; Saliva; Source; Tooth structure; United States National Institutes of Health; bone loss

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to evaluate a diagnostic test that will help to determine whether certain proteins released by bacteria/cells in patients' mouths and around patients' gums can be used to determine periodontal disease progression. These proteins can be found in fluids in the mouth (such as the saliva). These proteins may help to predict bone loss around teeth before it is detected by a dental x-ray.'

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是评估一种诊断测试，该测试将有助于确定患者口腔和牙龈周围的细菌/细胞释放的某些蛋白质是否可用于确定牙周病的进展。这些蛋白质可以在口腔液体（例如唾液）中找到。这些蛋白质可能有助于在牙科 X 射线检测到牙齿周围的骨质流失之前预测它。