HYPERGLYCEMIA-INDUCED INSULIN RESISTANCE IN SKELETAL MUSCLE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 本研究旨在探讨伴有糖尿病酮症酸中毒(DKA)和/或严重高血糖的肥胖非裔美国人(AA)骨骼肌高血糖诱导胰岛素抵抗的分子机制。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study seeks to determine the molecular mechanisms underlying hyperglycemia-induced insulin resistance in skeletal muscle in obese African-American (AA) with diabetic ketoacidosis (DKA) and/or severe hyperglycemia.