Training Program in Environmental Toxicology

 描述(由申请人提供) 环境因子在人类疾病的发展中起着重要作用。识别这种毒物并了解它们在疾病中的因果作用可以迅速用于风险评估和管理，并在预防、治疗和临床情景方面具有巨大的前景。这项申请申请资金，以继续纽约大学的环境和分子毒理学培训计划。具体地说，调查人员要求提供资金，以支持纽约大学环境健康科学研究生项目每年6名博士前实习生的津贴和学费。培训将解决环境健康中的广泛问题，从癌症、心肺疾病和其他与环境有关的疾病的致病分子机制，到开发可用于预测环境制剂对人类健康的不利影响的动物模型。拟议的毒理学培训计划的主要优势是培训教师的卓越素质和跨学科多样性，这将为博士后学员提供一个在具有杰出国际声誉的研究人员的实验室进行环境和分子毒理学研究的绝佳机会。这一培训计划的使命是培养富有创造力和独立的研究科学家，他们能够解决复杂的环境污染物暴露带来的问题，以及快速变化的物理环境的压力。

 DESCRIPTION (provided by applicant) Environmental agents play a significant role in the development of human disease. The identification of such toxicants and understanding their causal role in disease can rapidly be used in risk assessment and management and holds enormous promise in terms of preventive, therapeutic and clinical scenarios. This application requests funds to continue NYU's training Program in Environmental and Molecular Toxicology. Specifically, the investigators request funding to support the stipend and tuition of 6 pre-doctoral trainees annually in the NYU Graduate Program in Environmental Health Sciences. The training will address a broad spectrum of problems in environmental health, from the causative molecular mechanisms of cancer, cardiopulmonary diseases, and other environmentally-related disorders to the development of animal models which may be used for predicting the adverse effects of environmental agents on human health. The major strength of the proposed toxicology training program is the outstanding quality and interdisciplinary diversity of the training faculty, which wll provide the pre-doctoral trainees an excellent opportunity to conduct environmental and molecular toxicology research in laboratories of investigators with outstanding international reputations. The mission of this training program is to development creative and independent research scientists who can address the problems presented by complex exposures to environmental pollutants in combination with the stresses of a rapidly changing physical environment.