Data acquisition and analysis core

数据采集​​与分析核心

• 批准号: 7920926
• 负责人: GREGORY MCCARTHY
• 金额: $ 27.44万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7920926
• 关键词: Anatomy; Auditory; Bioinformatics; Blood; Brain; Brain imaging; Budgets; Clinical Practice Guideline; Collaborations; Computer software; Computers; Contracts; Data; Data Analyses; Databases; Development; Documentation; Epilepsy; Event-Related Potentials; Eye; Faculty; Functional Magnetic Resonance Imaging; Funding; Goals; Grant; Guidelines; Human; Image; Image Analysis; Information Systems; Libraries; Magnetic Resonance Imaging; Maintenance; Measurement; Operative Surgical Procedures; Oxygen; Principal Investigator; Program Research Project Grants; Psychophysics; Recruitment Activity; Research; Research Personnel; Resources; Running; Schedule; Science; Scientist; Screening procedure; Services; Site; Software Engineering; Software Tools; System; Techniques; Universities; Visual; auditory stimulus; data acquisition; novel; programs; research study; response; tool

The Data Acquisition and Analysis Core is both a service and development core that will support the data acquisition and analysis needs of all investigators. By consolidating support resources into this Core, we will achieve efficiencies in data acquisition and analysis and economies of scale that will enable us to increase our PPG from five to nine faculty investigators and to greatly expand our scientific scope. The Data Acquisition and Analysis Core has five major Aims. The first Aim is to provide direct services to all investigators within this Program Project Grant (PPG). These services include (1) a service for recruiting, screening, and scheduling all experimental subjects forfMRI experiments, (2) the provision of a PPGdedicated experimenter to supervise and run all experimental sessions (in addition to the certified MR technologist provided by the Brain Imaging and Analysis Center to acquire images for all studies), (3) the provision of a PPG-dedicated data analyst who will assess the quality of all MRI data using purpose-built software tools, and who will guide all fMRI data through all preprocessing steps of the image analysis pipeline. The second Aim is to support the acquisition of all intracranial event-related potential (ERP) studies performed at Yale University for all PPG investigators. The third Aim is to maintain all visual and auditory stimulus delivery systems, response manipulanda, eye trackers, experimental control computers, and experimental control software. The fourth Aim is to leverage the BIAC's participation in the NIH/NCRR's Bioinformatics Research Network (BIRN) consortium so that all software tools developed by BIRN scientists and software engineers are integrated into the PPG's data analysis pipeline. The fifth Aim is to develop a semi-automated system based for data documentation and data provenance that incorporates principles from the FDA's "Good Clinical Practices" guidelines.

数据采集和分析核心既是支持数据的服务核心，也是支持数据的开发核心 所有调查人员的采集和分析需求。通过将支持资源整合到此核心中，我们将 实现数据获取和分析的效率以及规模经济，这将使我们能够 我们的PPG从5名教员调查人员增加到9名，并极大地扩大了我们的科学范围。数据 收购和分析核心公司有五个主要目标。第一个目标是为所有 本计划项目拨款(PPG)内的调查人员。这些服务包括(1)招聘服务， 筛选和安排所有实验对象进行功能磁共振实验，(2)提供PPG专用 实验员监督和运行所有实验课程(除认证MR外 由脑成像和分析中心提供的技术专家为所有研究获取图像)，(3) 提供一名PPG专职数据分析师，他将使用专门构建的 软件工具，并将指导所有fMRI数据完成图像分析的所有预处理步骤 输油管道。第二个目标是支持获取所有的颅内事件相关电位(ERP)研究 在耶鲁大学为所有PPG调查人员表演。第三个目标是保持所有的视觉和听觉 刺激传递系统、反应操纵器、眼球追踪器、实验控制计算机和 实验控制软件。第四个目标是利用BIAC对NIH/NCRR的参与 生物信息学研究网络(BIRN)联盟，使BIRN科学家开发的所有软件工具 软件工程师被整合到PPG的数据分析管道中。第五个目标是开发一种 以数据文档和数据来源为基础的半自动系统，融合了原理 来自FDA的“良好临床实践”指南。