2010 Microbial Stress Response Gordon Research Conference

2010 微生物应激反应戈登研究会议

• 批准号: 7902698
• 负责人: Mark D Goulian
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7902698
• 关键词: Antibiotics; Bacteria; Biological; Biotechnology; Commit; Communities; Discipline; Disease; Ecology; Environment; Health; Human; Infection; Methods; Microbe; Molecular Genetics; Participant; Pharmaceutical Preparations; Play; Request for Proposals; Research; Resistance; Role; Scientist; Stress; System; Therapeutic; Toxin; Virulence; Woman; Work; abstracting; antimicrobial; biological adaptation to stress; college; combat; design; fighting; improved; insight; interest; meetings; member; microbial; pathogen; physical science; programs; symposium

DESCRIPTION (provided by applicant): This proposal requests partial support for the 2010 Microbial Stress Response Gordon Research Conference to be held July 18-23, 2010 at Mount Holyoke College, South Hadley, MA. This extraordinarily successful biannual conference attracts diverse scientists from the biological and physical sciences with broad interests in the mechanisms that bacteria employ to sense and respond to various forms of stress. The 2010 conference will have a strong representation of stress responses of pathogens as well as stress in the context of ecology and biotechnology. Stress responses associated with antimicrobials, both their mechanisms of action and resistance, will be a major theme. In addition to a session devoted to antibiotic stress and survival, numerous talks in other sessions will cover aspects of antimicrobials and related toxins. Computational and systems-level approaches to stress-responses will also be well represented and integrated throughout various sessions. In addition to the invited speakers, speakers will be selected for short talks from submitted abstracts. This will provide an opportunity for young scientists to present their work. The organizers are also committed to the strong tradition of diversity that has characterized this meeting and will work to include women and members of underrepresented groups as speakers and participants. This meeting will play a strategic role in advancing microbial research by integrating cutting edge, genetic, molecular, and computational approaches to the study of microbial systems and their stress responses. The meeting provides an unparalleled venue to bring together scientists from diverse disciplines with the aim of uncovering the principals governing microbial survival and adaptation in stressful environments. Stress responses are critical for pathogens to colonize hosts, initiate virulence programs, and resist antimicrobial treatments. Thus, the insights and new directions stimulated by this meeting will help the community to develop new methods to fight off pathogens and improve human health. A better understanding of the mechanisms that microbes use to survive and adapt to stress will provide key insights into the means by which pathogens are able to colonize and cause disease in humans, and resist antimicrobial treatments. This will aid in the design of new drugs and therapeutic strategies for combating infection and the spread of disease.

描述（由申请人提供）：本提案要求部分支持将于2010年7月18日至23日在马萨诸塞州南哈德利的蒙特霍利奥克学院举行的2010年微生物应激反应戈登研究会议。这个非常成功的两年一度的会议吸引了来自生物和物理科学的不同科学家，他们对细菌用来感知和应对各种形式的压力的机制有着广泛的兴趣。2010年的会议将有一个强大的代表性的压力反应的病原体以及压力的背景下，生态和生物技术。与抗菌剂相关的应激反应，包括其作用机制和耐药性，将是一个主要主题。除了一个专门讨论抗生素压力和生存的会议外，其他会议的许多演讲将涵盖抗菌素和相关毒素的各个方面。计算和系统级的方法来应对压力也将得到很好的体现，并整合在各个会议。除了受邀演讲者外，还将从提交的摘要中挑选演讲者进行简短的演讲。这将为年轻科学家提供展示其工作的机会。组织者还致力于保持作为本次会议特点的强大的多样性传统，并将努力让妇女和代表性不足的群体成员作为发言者和与会者。本次会议将通过整合尖端，遗传，分子和计算方法来研究微生物系统及其应激反应，在推进微生物研究方面发挥战略作用。会议提供了一个无与伦比的场所，汇集了来自不同学科的科学家，旨在揭示在压力环境中微生物生存和适应的原则。应激反应对于病原体在宿主中定殖、启动毒力程序和抵抗抗微生物治疗至关重要。因此，本次会议激发的见解和新方向将有助于社区开发新方法来对抗病原体并改善人类健康。更好地了解微生物用于生存和适应压力的机制将为病原体能够在人类中定植和引起疾病并抵抗抗菌治疗的手段提供关键见解。这将有助于设计新的药物和治疗战略，以防治感染和疾病的传播。