INVESTIGATIONS OF A NEW TYPE ENDOCRINE DISRUPTOR, TCC

新型内分泌干扰物 TCC 的研究

• 批准号: 7959062
• 负责人: Bill Lee Lasley
• 金额: $ 3.56万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959062
• 关键词: Address; Adverse effects; Animal Model; Benign Prostatic Hypertrophy; California; Computer Retrieval of Information on Scientific Projects Database; Data; Endocrine; Exposure to; Funding; Grant; Human; Institution; Investigation; Malignant Neoplasms; Organ; Primates; Research; Research Personnel; Resources; Rodent; Self Care; Source; United States National Institutes of Health; human disease; nonhuman primate; reproductive; reproductive development; reproductive function; triclocarban

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of the project is to investigate the effects of triclocarban (TCC), a new type endocrine disruptor on reproductive function, reproductive development and the potential effects on inducing cancer in reproductive organs. The results of this project will address concerns relating to the potential effects of adverse effects in humans as a result of exposure to TCC-containing personal care products. The studies using the non-human primate animal model are necessary to provide data that is more relevant to human diseases such as benign prostatic hyperplasia (BPH), compared to traditional data collected with rodent animal models.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本项目的目的是研究新型内分泌干扰物三氯卡班（TCC）对生殖功能、生殖发育的影响以及诱发生殖器官癌症的潜在作用。 该项目的结果将解决与接触含TCC的个人护理产品对人体产生的潜在不良影响有关的问题。 与使用啮齿动物模型收集的传统数据相比，使用非人灵长类动物模型的研究对于提供与良性前列腺增生（BPH）等人类疾病更相关的数据是必要的。