Coordinating Center for Beta Cell Biology Consortium

β细胞生物学联盟协调中心

基本信息

  • 批准号:
    8010566
  • 负责人:
  • 金额:
    $ 12.96万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-03-08 至 2011-02-28
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This application is a response to NOT-DK-04-501 and a letter RFA for Vanderbilt University to continue to serve as the Coordinating Center (CC) for the Beta Cell Biology Consortium (BCBC), a team science initiative that has been in existence since September 2001. The mission of the BCBC, as defined by RFA DK-01-014, is to facilitate interdisciplinary approaches that will advance our understanding of pancreatic islet development and function with the long-term goal of developing a cell-based therapy for insulin delivery. In the second phase of the BCBC, whose objectives have been defined by RFAs DK-04-017 and DK-04-018 as well as the letter RFA to Vanderbilt, the BCBC will undertake a variety of investigator-initiated studies while also placing a major emphasis on reagent-generating activities. Thus, for this team of scientists to be able to generate new antibodies and genetically modified mice, while also maintaining focus on the scientific needs that lie at the heart of determining how to develop a cell-based therapy for insulin delivery, a CC has been developed over the past two years. The CC is now fully positioned to provide financial, organizational, and informatic support for the wide variety of scientific activities that will be encompassed by the BCBC. The primary objectives of the CC are to 1) facilitate interactions and communication by organizing meetings and retreats, distributing announcements, and maintaining a website with databases of vital research resources; 2) support research within the BCBC by enriching existing core facilities and developing new cores; 3) to jumpstart new research by young investigators through a Pilot and Feasibility (P&F) Grant Program; and 4) to bring different groups of scientists together within the BCBC by establishing a Program of Collaborative Bridging Projects. It is expected that, through a combination of both new and currently existing programs and activities, the CC will continue to stimulate participating scientists to develop new reagents and strategies that will serve as a platform for further discovery and progress within the beta cell biology field.
描述(由申请人提供): 此申请是对NOT-DK-04-501的回应,也是范德比尔特大学继续担任Beta细胞生物学联盟(BCBC)协调中心(CC)的信函,BCBC是自2001年9月以来一直存在的团队科学倡议。根据RFA DK-01-014的定义,BCBC的使命是促进跨学科方法,以促进我们对胰岛发育和功能的了解,并以开发基于细胞的胰岛素输送疗法为长期目标。在BCBC的第二阶段,其目标已由RFA DK-04-017和DK-04-018以及RFA致Vanderbilt的信确定,BCBC将开展各种由调查员发起的研究,同时也将主要重点放在试剂生成活动上。因此,为了让这个科学家团队能够产生新的抗体和转基因小鼠,同时保持对科学需求的关注,这些需求是决定如何开发基于细胞的胰岛素输送疗法的核心,在过去的两年里已经开发出了CC。CC现在完全有能力为BCBC所涵盖的各种科学活动提供资金、组织和信息方面的支持。CC的主要目标是:1)通过组织会议和务虚会、发布公告和维护一个具有重要研究资源数据库的网站来促进互动和沟通;2)通过丰富现有的核心设施和开发新的核心来支持BCBC内的研究;3)通过试点和可行性(P&F)资助计划启动年轻研究人员的新研究;以及4)通过建立合作桥梁项目计划将不同的科学家群体聚集在BCBC内。预计,通过新的和目前存在的计划和活动的结合,CC将继续鼓励参与的科学家开发新的试剂和策略,作为在β细胞生物学领域进一步发现和进步的平台。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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MARK A MAGNUSON其他文献

MARK A MAGNUSON的其他文献

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{{ truncateString('MARK A MAGNUSON', 18)}}的其他基金

Coordinating Center for Beta Cell Biology Consortium
β细胞生物学联盟协调中心
  • 批准号:
    8121183
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Transgenic Mouse
转基因小鼠
  • 批准号:
    8180600
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Genetic control of pancreatic endocrine cell development
胰腺内分泌细胞发育的遗传控制
  • 批准号:
    7993178
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Genetic control of pancreatic endocrine cell development
胰腺内分泌细胞发育的遗传控制
  • 批准号:
    8717642
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Genetic control of pancreatic endocrine cell development
胰腺内分泌细胞发育的遗传控制
  • 批准号:
    8522192
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Genetic control of pancreatic endocrine cell development
胰腺内分泌细胞发育的遗传控制
  • 批准号:
    8144905
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Genetic control of pancreatic endocrine cell development
胰腺内分泌细胞发育的遗传控制
  • 批准号:
    8316316
  • 财政年份:
    2010
  • 资助金额:
    $ 12.96万
  • 项目类别:
Coordinating Center for Beta Cell Biology Consortium
β细胞生物学联盟协调中心
  • 批准号:
    7825081
  • 财政年份:
    2009
  • 资助金额:
    $ 12.96万
  • 项目类别:
EFFECTS OF LIVER SPECIFIC KNOCKOUT OF PEPCK ON GLUCOSE METABOLISM
肝脏特异性敲除 PEPCK 对葡萄糖代谢的影响
  • 批准号:
    7724113
  • 财政年份:
    2008
  • 资助金额:
    $ 12.96万
  • 项目类别:
EFFECTS OF LIVER SPECIFIC KNOCKOUT OF PEPCK ON GLUCOSE METABOLISM
肝脏特异性敲除 PEPCK 对葡萄糖代谢的影响
  • 批准号:
    7600847
  • 财政年份:
    2007
  • 资助金额:
    $ 12.96万
  • 项目类别:

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