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Molecular subtype specific therapy in high grade serous ovarian cancer

Molecular subtype specific therapy in high grade serous ovarian cancer
高级别浆液性卵巢癌的分子亚型特异性治疗
批准号：
nhmrc : 1081178
负责人：
A/Pr Clare Scott
金额：
$55.49万
依托单位：
The University of Melbourne
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2015
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2015-01-01 至 2017-12-31
来源：
https://researchdata.edu.au/molecular-subtype-specific-ovarian-cancer/518790
关键词：
Molecularsubtypespecifictherapygrade

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英文摘要
High grade serous ovarian cancer (HGSC) is the most common type of ovarian cancer, accounting for about two thirds of all deaths from the disease.Several years ago we identified distinct subtypes of HGSC (C1, C2, C4, C5) based on patterns of gene activity. We found that women with the C5 subtype generally had poor survival, and we mapped genes that were specifically active in C5 tumours. In this application we aim to develop therapies that are specifically targeted to the C5 HGSC.
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Exploring the DNA repair capacity of oocytes
  • 批准号：
    nhmrc : 1100219
  • 项目类别：
    Project Grants
  • 资助金额：
    $51.1万
  • 财政年份：
    2016
  • 负责人：
    A/Pr Clare Scott
  • 依托单位：
    Monash University
Engineering MYCN models of high-grade serous ovarian cancer (HGSC)
Tailoring targeted therapy to DNA repair-defective High-Grade Serous Ovarian Cancer
Improving outcomes for women diagnosed with mucinous ovarian cancer
  • 批准号：
    nhmrc : 1045783
  • 项目类别：
    Project Grants
  • 资助金额：
    $39.89万
  • 财政年份：
    2013
  • 负责人：
    A/Pr Clare Scott
  • 依托单位：
    The University of Melbourne
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